Metapathway biotransformation (WP1251)

last edited

Authors

MaintBot, Khanspers, Ddigles, and Egonw

Cited In

Organism

Mus musculus

Communities

Annotations

Pathway Ontology: cellular detoxification pathway

Participants

Label Type Compact Identifier
GSTA5 GeneProduct None
Sulfotransferase GeneProduct None
Cyp4b1 GeneProduct ensembl:ENSMUSG00000028713
Ndst4 GeneProduct ensembl:ENSMUSG00000027971
GSTA4 GeneProduct ncbigene:14860
Akr7a5 GeneProduct ensembl:ENSMUSG00000028743
Nat12 GeneProduct ensembl:ENSMUSG00000036282
NAT1 GeneProduct None
Flavin monooxygenase GeneProduct None
SULT1C2 GeneProduct ncbigene:69083
UGT1A5 GeneProduct ncbigene:394433
NAT2 GeneProduct ncbigene:17961
Substrate-SH Metabolite chebi:29256
Ugt1a5 GeneProduct ncbigene:394433
Cyp39a1 GeneProduct ensembl:ENSMUSG00000023963
Cyp27a1 GeneProduct ensembl:ENSMUSG00000026170
CYP2D6 GeneProduct None
Ndst2 GeneProduct ensembl:ENSMUSG00000039308
Cyp2u1 GeneProduct ensembl:ENSMUSG00000027983
CYP450 GeneProduct None
Fmo5 GeneProduct ensembl:ENSMUSG00000028088
Ndst3 GeneProduct ensembl:ENSMUSG00000027977
Hs6st1 GeneProduct ensembl:ENSMUSG00000045216
Gstt2 GeneProduct ensembl:ENSMUSG00000033318
UGT1A7 GeneProduct None
Cyp4f18 GeneProduct ensembl:ENSMUSG00000003484
AKR1C2 GeneProduct None
Cyp4x1 GeneProduct ensembl:ENSMUSG00000047155
Hs3st1 GeneProduct ensembl:ENSMUSG00000051022
Mgst2 GeneProduct ensembl:ENSMUSG00000074604
HS3ST3A1 GeneProduct ncbigene:15478
Amino acid acyltransferase GeneProduct None
CYP2A7 GeneProduct None
Cyp4f39 GeneProduct ensembl:ENSMUSG00000061126
Gpx1 GeneProduct ensembl:ENSMUSG00000063856
Substrate-NH2 Metabolite chebi:50047
N-acetyltransferase GeneProduct None
Chst7 GeneProduct ensembl:ENSMUSG00000037347
Tpmt GeneProduct ensembl:ENSMUSG00000021376
Glyat GeneProduct ensembl:ENSMUSG00000063683
Hnmt GeneProduct ensembl:ENSMUSG00000026986
Baat GeneProduct ensembl:ENSMUSG00000039653
Fmo3 GeneProduct ensembl:ENSMUSG00000026691
CYP2B6 GeneProduct None
CYP2C19 GeneProduct None
Chst1 GeneProduct ensembl:ENSMUSG00000027221
GSTA1 GeneProduct ncbigene:14857
Cyp24a1 GeneProduct ensembl:ENSMUSG00000038567
Chst3 GeneProduct ensembl:ENSMUSG00000057337
UGT1A10 GeneProduct ncbigene:394430
CYP4F12 GeneProduct None
UGT2B4 GeneProduct None
Sult1b1 GeneProduct ensembl:ENSMUSG00000029269
UGT1A9 GeneProduct ncbigene:394434
CYP27C1 GeneProduct None
CYP2A6 GeneProduct None
SULT1C4 GeneProduct None
Cyp46a1 GeneProduct ensembl:ENSMUSG00000021259
CYP2C9 GeneProduct None
Substrate=O Metabolite chebi:36586
Cyp4v3 GeneProduct ensembl:ENSMUSG00000079057
Nat6 GeneProduct ensembl:ENSMUSG00000079334
GSTM4 GeneProduct ncbigene:14865
Gpx2 GeneProduct ensembl:ENSMUSG00000042808
CYP11B1 GeneProduct ncbigene:110115
Substrate-Aa Metabolite None
CYP2C18 GeneProduct None
CYP4F11 GeneProduct None
GLYATL1 GeneProduct None
Substrate-CH3 Metabolite None
Ugt1a1 GeneProduct ncbigene:394436
Cyp1a2 GeneProduct ensembl:ENSMUSG00000032310
Akr1b3 GeneProduct ensembl:ENSMUSG00000001642
Hs3st2 GeneProduct ensembl:ENSMUSG00000046321
Nat14 GeneProduct ensembl:ENSMUSG00000035285
Gpx3 GeneProduct ensembl:ENSMUSG00000018339
Cyp1b1 GeneProduct ensembl:ENSMUSG00000024087
GLYATL2 GeneProduct None
Gsto1 GeneProduct ensembl:ENSMUSG00000025068
Cyp20a1 GeneProduct ensembl:ENSMUSG00000049439
Cyp2s1 GeneProduct ensembl:ENSMUSG00000040703
Sult1e1 GeneProduct ensembl:ENSMUSG00000029272
Cyp19a1 GeneProduct ensembl:ENSMUSG00000032274
Cyp21a1 GeneProduct ncbigene:13079
AKR7A3 GeneProduct None
Cyp26c1 GeneProduct ensembl:ENSMUSG00000062432
SULT2A1 GeneProduct ncbigene:20859
Hs6st2 GeneProduct ensembl:ENSMUSG00000062184
Cyp27b1 GeneProduct ensembl:ENSMUSG00000006724
Cyp26b1 GeneProduct ensembl:ENSMUSG00000063415
Gstt1 GeneProduct ensembl:ENSMUSG00000001663
Akr1a4 GeneProduct ensembl:ENSMUSG00000028692
Fmo1 GeneProduct ensembl:ENSMUSG00000040181
UGT2B7 GeneProduct None
Nat5 GeneProduct ensembl:ENSMUSG00000002728
UGT2A2 GeneProduct ncbigene:552899
Inmt GeneProduct ensembl:ENSMUSG00000003477
Nnmt GeneProduct ensembl:ENSMUSG00000032271
Gstm7 GeneProduct ensembl:ENSMUSG00000004035
AKR1C3 GeneProduct None
Aldo-keto reductase GeneProduct None
Methyltransferase GeneProduct None
AC161058.2-1 GeneProduct ensembl:ENSMUSG00000029541
Nat10 GeneProduct ensembl:ENSMUSG00000027185
Chst11 GeneProduct ensembl:ENSMUSG00000034612
Chst9 GeneProduct ncbigene:71367
SULT1C3 GeneProduct None
Gal3st4 GeneProduct ensembl:ENSMUSG00000075593
CYP3A7 GeneProduct None
UGT2B15 GeneProduct None
UGT2B11 GeneProduct None
Cyp7a1 GeneProduct ensembl:ENSMUSG00000028240
Gstz1 GeneProduct ensembl:ENSMUSG00000021033
Substrate-O-R Metabolite chebi:25698
CYP4F2 GeneProduct None
Chst2 GeneProduct ensembl:ENSMUSG00000033350
Cyp2f2 GeneProduct ensembl:ENSMUSG00000052974
Gal3st1 GeneProduct ensembl:ENSMUSG00000049721
Hs3st5 GeneProduct ensembl:ENSMUSG00000044499
Gstk1 GeneProduct ensembl:ENSMUSG00000029864
Gal3st3 GeneProduct ensembl:ENSMUSG00000047658
Hs2st1 GeneProduct ensembl:ENSMUSG00000040151
Cyp8b1 GeneProduct ensembl:ENSMUSG00000050445
Cyp1a1 GeneProduct ensembl:ENSMUSG00000032315
Glucuronosyltransferase GeneProduct None
Gsr GeneProduct ensembl:ENSMUSG00000031584
Substrate-Ac Metabolite None
Sult4a1 GeneProduct ensembl:ENSMUSG00000018865
Substrate-OH Metabolite chebi:30879
Hs6st3 GeneProduct ensembl:ENSMUSG00000053465
CYP11B2 GeneProduct ncbigene:13072
GSTM5 GeneProduct ncbigene:14866
CYP4Z1 GeneProduct None
Substrate-Gl Metabolite None
AKR1C4 GeneProduct None
Ugt2a2 GeneProduct ensembl:ENSMUSG00000029268
Ndst1 GeneProduct ensembl:ENSMUSG00000054008
AKR1C1 GeneProduct None
Kcnab1 GeneProduct ensembl:ENSMUSG00000027827
Gstcd GeneProduct ensembl:ENSMUSG00000028018
AC122521.4 GeneProduct ensembl:ENSMUSG00000056643
Cyp7b1 GeneProduct ensembl:ENSMUSG00000039519
Cyp11a1 GeneProduct ensembl:ENSMUSG00000032323
CYP2C8 GeneProduct None
Ugt2a3 GeneProduct ensembl:ENSMUSG00000035780
Chst10 GeneProduct ensembl:ENSMUSG00000026080
Sult1c2 GeneProduct ensembl:ENSMUSG00000023122
Ephx1 GeneProduct ensembl:ENSMUSG00000038776
Nat9 GeneProduct ensembl:ENSMUSG00000015542
Nat8l GeneProduct ensembl:ENSMUSG00000048142
Sult1a1 GeneProduct ensembl:ENSMUSG00000030711
Nat13 GeneProduct ensembl:ENSMUSG00000022698
Hs3st4 GeneProduct ensembl:ENSMUSG00000078591
UGT1A6 GeneProduct None
Gpx4 GeneProduct ensembl:ENSMUSG00000075706
Cyp2r1 GeneProduct ensembl:ENSMUSG00000030670
HS3ST3B1 GeneProduct ncbigene:54710
Sult2b1 GeneProduct ensembl:ENSMUSG00000003271
Gss GeneProduct ensembl:ENSMUSG00000027610
Gpx5 GeneProduct ensembl:ENSMUSG00000004344
Substrate-SO3H Metabolite None
Glutathione transferase GeneProduct None
CYP4F8 GeneProduct None
Ephx2 GeneProduct ensembl:ENSMUSG00000022040
Chst5 GeneProduct ensembl:ENSMUSG00000031952
UGT2B28 GeneProduct None
CYP3A4 GeneProduct None
GSTM1 GeneProduct ncbigene:14862
Kcnab3 GeneProduct ensembl:ENSMUSG00000018470
Fmo2 GeneProduct ensembl:ENSMUSG00000040170
GSTA3 GeneProduct ncbigene:14859
Kcnab2 GeneProduct ensembl:ENSMUSG00000028931
AC140307.3-1 GeneProduct ensembl:ENSMUSG00000024764
Fmo4 GeneProduct ensembl:ENSMUSG00000026692
Cyp26a1 GeneProduct ensembl:ENSMUSG00000024987
Sult1a1 GeneProduct ensembl:ENSMUSG00000030711
Cyp2e1 GeneProduct ensembl:ENSMUSG00000025479
Chst14 GeneProduct ncbigene:72136
AC154274.1-1 GeneProduct ensembl:ENSMUSG00000038045
Hs3st6 GeneProduct ensembl:ENSMUSG00000039628
Cyp17a1 GeneProduct ensembl:ENSMUSG00000003555
Chst4 GeneProduct ensembl:ENSMUSG00000035930
Mgst1 GeneProduct ensembl:ENSMUSG00000008540
UGT2B17 GeneProduct None
Sult1a1 GeneProduct ensembl:ENSMUSG00000030711
AKR1B10 GeneProduct ncbigene:67861
NAT8 GeneProduct ncbigene:68396
CYP3A43 GeneProduct None
Sult1a1 GeneProduct ensembl:ENSMUSG00000030711
Ugt1a10 GeneProduct ensembl:ENSMUSG00000054545
CYP3A5 GeneProduct None
GSTA2 GeneProduct ncbigene:14858
GSTP1 GeneProduct ncbigene:14870
Comt1 GeneProduct ensembl:ENSMUSG00000000326
Chst5 GeneProduct ensembl:ENSMUSG00000031952
Substrate-SG Metabolite None
Xenobiotic substrate Metabolite None
Ugt1a2 GeneProduct ncbigene:22236
CYP2J2 GeneProduct None
Mgst3 GeneProduct ensembl:ENSMUSG00000026688
Akr1d1 GeneProduct ensembl:ENSMUSG00000038641
Gsto2 GeneProduct ensembl:ENSMUSG00000025069
Gstm5 GeneProduct ensembl:ENSMUSG00000004032
GAL3ST2 GeneProduct ncbigene:381334
Gstt2 GeneProduct ensembl:ENSMUSG00000033318
Chst8 GeneProduct ensembl:ENSMUSG00000060402
CYP2A13 GeneProduct None
Cyp51 GeneProduct ensembl:ENSMUSG00000001467
Chst12 GeneProduct ensembl:ENSMUSG00000036599

References