Oxidation by cytochrome P450 (WP1274)

Oxidation of a substrate by Cytochrome P450. Adapted from Niesink et al., Chapter 3, p. 47-48.
last edited

Authors

MaintBot, Christine Chichester, Khanspers, and Eweitz

Cited In

Organism

Mus musculus

Communities

Annotations

Pathway Ontology: phase I biotransformation pathway via cytochrome P450

Participants

Label Type Compact Identifier
Cyp26a1 GeneProduct ensembl:ENSMUSG00000024987
CYP4F11 GeneProduct None
Cyb5b GeneProduct ensembl:ENSMUSG00000031924
CYP GeneProduct None
NADPH Metabolite chebi:16474
CYP2C8 GeneProduct None
CYP2B6 GeneProduct None
Cyb5r1 GeneProduct ensembl:ENSMUSG00000026456
Cyp4f39 GeneProduct ensembl:ENSMUSG00000061126
Cyb5 GeneProduct ensembl:ENSMUSG00000024646
CYP GeneProduct None
O2 Metabolite hmdb:HMDB0001377
CYP4Z1 GeneProduct None
CYP GeneProduct None
CYP4F8 GeneProduct None
Cyp1b1 GeneProduct ensembl:ENSMUSG00000024087
CYP2C18 GeneProduct None
Cyb5r4 GeneProduct ensembl:ENSMUSG00000032872
CYP4A22 GeneProduct None
O2 Metabolite hmdb:HMDB0001377
Cyb5b GeneProduct ensembl:ENSMUSG00000031924
Cyb5r2 GeneProduct ensembl:ENSMUSG00000048065
Fe3+ Metabolite chebi:29034
Cyp11b1 GeneProduct ncbigene:110115
Cyp27b1 GeneProduct ensembl:ENSMUSG00000006724
CYP2A6 GeneProduct None
Cyp4f18 GeneProduct ensembl:ENSMUSG00000003484
Cyp26c1 GeneProduct ensembl:ENSMUSG00000062432
CYP GeneProduct None
Water Metabolite hmdb:HMDB0002111
Cyp51 GeneProduct ensembl:ENSMUSG00000001467
activated O2 Metabolite None
CYP4A11 GeneProduct None
CYP2A7 GeneProduct None
Cyb5b GeneProduct ensembl:ENSMUSG00000031924
Cyp7b1 GeneProduct ensembl:ENSMUSG00000039519
CYP GeneProduct None
Cyp19a1 GeneProduct ensembl:ENSMUSG00000032274
Cyp21a1 GeneProduct ensembl:ENSMUSG00000024365
CYP3A43 GeneProduct None
Cyp26b1 GeneProduct ensembl:ENSMUSG00000063415
Cyp7a1 GeneProduct ensembl:ENSMUSG00000028240
CYP3A4 GeneProduct None
AC161058.2-1 GeneProduct ensembl:ENSMUSG00000029541
Substrate GeneProduct None
Cyp8b1 GeneProduct ensembl:ENSMUSG00000050445
Substrate-OH GeneProduct None
NADP+ Metabolite chebi:18009
Cyp2s1 GeneProduct ensembl:ENSMUSG00000040703
Cyp39a1 GeneProduct ensembl:ENSMUSG00000023963
Cyp2r1 GeneProduct ensembl:ENSMUSG00000030670
Cyp46a1 GeneProduct ensembl:ENSMUSG00000021259
Cyp4b1 GeneProduct ensembl:ENSMUSG00000028713
Cyp1a2 GeneProduct ensembl:ENSMUSG00000032310
Cyp4v3 GeneProduct ensembl:ENSMUSG00000079057
Cyp2u1 GeneProduct ensembl:ENSMUSG00000027983
CYP2J2 GeneProduct None
CYP2G1P GeneProduct None
Cyp4x1 GeneProduct ensembl:ENSMUSG00000047155
Fe3+ Metabolite chebi:29034
Cyp51 GeneProduct ensembl:ENSMUSG00000001467
Cyp2e1 GeneProduct ensembl:ENSMUSG00000025479
Cyp11a1 GeneProduct ensembl:ENSMUSG00000032323
Cyp20a1 GeneProduct ensembl:ENSMUSG00000049439
Fe3+ Metabolite chebi:29034
Por GeneProduct ensembl:ENSMUSG00000005514
Cyp17a1 GeneProduct ensembl:ENSMUSG00000003555
Fe2+ Metabolite chebi:29033
CYP4F2 GeneProduct None
Fe2+ Metabolite chebi:29033
Substrate GeneProduct None
CYP3A5 GeneProduct None
Cyp27a1 GeneProduct ensembl:ENSMUSG00000026170
CYP2A13 GeneProduct None
Substrate GeneProduct None
Cyp2f2 GeneProduct ensembl:ENSMUSG00000052974
Fe2+ Metabolite chebi:29033
Substrate GeneProduct None
CYP2C19 GeneProduct None
CYP27C1 GeneProduct None
Fe3+ Metabolite chebi:29034
Cyb5r3 GeneProduct ensembl:ENSMUSG00000018042
Cyp11b2 GeneProduct ncbigene:13072
Cyp24a1 GeneProduct ensembl:ENSMUSG00000038567
CYP2C9 GeneProduct None
CYP4F12 GeneProduct None
Substrate GeneProduct None
Cyp1a1 GeneProduct ensembl:ENSMUSG00000032315
Fe2+ Metabolite chebi:29033
Cyb5 GeneProduct ensembl:ENSMUSG00000024646
Cyb5 GeneProduct ensembl:ENSMUSG00000024646
CYP2D6 GeneProduct None
CYP3A7 GeneProduct None
NADH Metabolite chebi:16908
NAD+ Metabolite chebi:15846

References