EBV LMP1 signaling (WP1278)

based on science-slides...
last edited

Authors

MaintBot and Christine Chichester

Cited In

Organism

Rattus norvegicus

Communities

Annotations

Pathway Ontology: Epstein-Barr virus infection pathway

Participants

Label Type Compact Identifier
NP_001100528.1 GeneProduct ensembl:ENSRNOG00000008441
Nfkb2 GeneProduct ensembl:ENSRNOG00000019311
Mapk8 GeneProduct ensembl:ENSRNOG00000020155
Tnf GeneProduct ensembl:ENSRNOG00000000837
Rela GeneProduct ensembl:ENSRNOG00000030888
Pdlim7 GeneProduct ensembl:ENSRNOG00000013653
Rela GeneProduct ensembl:ENSRNOG00000030888
Nfkb2 GeneProduct ensembl:ENSRNOG00000019311
I-Kappa-B GeneProduct None
IL8 GeneProduct None
Rela GeneProduct ensembl:ENSRNOG00000030888
Tradd GeneProduct ensembl:ENSRNOG00000015179
Ifnb1 GeneProduct ensembl:ENSRNOG00000006268
Ikbkb GeneProduct ensembl:ENSRNOG00000019073
NP_001101224.1 GeneProduct ensembl:ENSRNOG00000004639
NP_001101058.1 GeneProduct ensembl:ENSRNOG00000022485
NP_001101390.1 GeneProduct ensembl:ENSRNOG00000005724
Nfkb1 GeneProduct ensembl:ENSRNOG00000023258
Irak1_predicted GeneProduct ensembl:ENSRNOG00000037263
TRAF1 GeneProduct None
Nfkb1 GeneProduct ensembl:ENSRNOG00000023258
Ccl5 GeneProduct ensembl:ENSRNOG00000010906
NP_001101771.1 GeneProduct ensembl:ENSRNOG00000003278
NP_001101390.1 GeneProduct ensembl:ENSRNOG00000005724
Rela GeneProduct ensembl:ENSRNOG00000030888
Chuk GeneProduct ncbigene:309361
Ikbkg GeneProduct ensembl:ENSRNOG00000037237
Rela GeneProduct ensembl:ENSRNOG00000030888
Nfkb1 GeneProduct ensembl:ENSRNOG00000023258
Ccl20 GeneProduct ensembl:ENSRNOG00000015992
Mapk1 GeneProduct ensembl:ENSRNOG00000001849
Rela GeneProduct ensembl:ENSRNOG00000030888
I-Kappa-B GeneProduct None
Hsp90aa1 GeneProduct ncbigene:299331
SFC complex GeneProduct None
Nfkb1 GeneProduct ensembl:ENSRNOG00000023258

References

  1. Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, et al. TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB. J Biol Chem. 2006 Mar 24;281(12):7863–72. PubMed Europe PMC Scholia
  2. Song Y-J, Jen K-Y, Soni V, Kieff E, Cahir-McFarland E. IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2689–94. PubMed Europe PMC Scholia
  3. Lee J-S, Lee J-Y, Son JW, Oh J-H, Shin D-M, Yuk J-M, et al. Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis. Scand J Immunol. 2008 Jan;67(1):77–85. PubMed Europe PMC Scholia
  4. Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L, et al. Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB. J Leukoc Biol. 2008 Mar;83(3):648–62. PubMed Europe PMC Scholia