Metapathway biotransformation (WP1286)

last edited

Authors

MaintBot, Khanspers, and Ddigles

Cited In

Organism

Rattus norvegicus

Communities

Annotations

Pathway Ontology: cellular detoxification pathway

Participants

Label Type Compact Identifier
GSTA5 GeneProduct None
Sulfotransferase GeneProduct None
Cyp4b1 GeneProduct ensembl:ENSRNOG00000009741
Ndst4_predicted GeneProduct ensembl:ENSRNOG00000009577
GSTA4 GeneProduct ncbigene:300850
Akr7a2 GeneProduct ensembl:ENSRNOG00000017780
NP_001102569.1 GeneProduct ensembl:ENSRNOG00000014192
NAT1 GeneProduct ncbigene:116631
Flavin monooxygenase GeneProduct None
SULT1C2 GeneProduct ncbigene:171072
Ugt1a3 GeneProduct ncbigene:396551
NAT2 GeneProduct ncbigene:116632
Substrate-SH Metabolite None
Ugt1a5 GeneProduct ncbigene:574523
NP_001100363.1 GeneProduct ensembl:ENSRNOG00000010519
Cyp27a1 GeneProduct ensembl:ENSRNOG00000017188
CYP2D6 GeneProduct None
NP_001099210.1 GeneProduct ensembl:ENSRNOG00000027171
Cyp2u1 GeneProduct ensembl:ENSRNOG00000011053
CYP450 GeneProduct None
Fmo5 GeneProduct ensembl:ENSRNOG00000018076
Ndst3_predicted GeneProduct ensembl:ENSRNOG00000015781
NP_001101680.1 GeneProduct ensembl:ENSRNOG00000014516
Gstt2 GeneProduct ensembl:ENSRNOG00000028188
UGT1A7 GeneProduct None
Cyp4f18 GeneProduct ensembl:ENSRNOG00000015751
AKR1C2 GeneProduct None
CYP4X1 GeneProduct ncbigene:246767
Hs3st1 GeneProduct ensembl:ENSRNOG00000010598
Mgst2 GeneProduct ensembl:ENSRNOG00000013296
HS3ST3A1 GeneProduct ncbigene:363618
Amino acid acyltransferase GeneProduct None
CYP2A7 GeneProduct None
Cyp4f39_predicted GeneProduct ensembl:ENSRNOG00000029478
GPX1 GeneProduct ncbigene:24404
Substrate-NH2 Metabolite None
N-acetyltransferase GeneProduct None
Chst7 GeneProduct ensembl:ENSRNOG00000004258
Tpmt GeneProduct ensembl:ENSRNOG00000016468
Glyat GeneProduct ensembl:ENSRNOG00000012142
Hnmt GeneProduct ensembl:ENSRNOG00000005223
Baat GeneProduct ensembl:ENSRNOG00000007395
Fmo3 GeneProduct ensembl:ENSRNOG00000003620
CYP2B6 GeneProduct None
CYP2C19 GeneProduct None
Chst1 GeneProduct ensembl:ENSRNOG00000007989
GSTA1 GeneProduct None
Cyp24a1 GeneProduct ensembl:ENSRNOG00000013062
Chst3 GeneProduct ensembl:ENSRNOG00000000572
UGT1A10 GeneProduct None
CYP4F12 GeneProduct None
UGT2B4 GeneProduct None
Sult1b1 GeneProduct ensembl:ENSRNOG00000001967
UGT1A9 GeneProduct ncbigene:396552
CYP27C1 GeneProduct None
CYP2A6 GeneProduct None
SULT1C4 GeneProduct None
NP_001102193.1 GeneProduct ensembl:ENSRNOG00000007147
CYP2C9 GeneProduct None
Substrate=O Metabolite None
CYP4V2 GeneProduct None
NAT6 GeneProduct None
MGC108896 GeneProduct ensembl:ENSRNOG00000019221
GPX2 GeneProduct ncbigene:29326
CYP11B1 GeneProduct ncbigene:500892
Substrate-Aa Metabolite None
CYP2C18 GeneProduct None
CYP4F11 GeneProduct None
GLYATL1 GeneProduct None
Substrate-CH3 Metabolite None
Ugt1a1 GeneProduct ncbigene:24861
Cyp1a2 GeneProduct ensembl:ENSRNOG00000016173
AKR1B1 GeneProduct ncbigene:24192
Hs3st2 GeneProduct ensembl:ENSRNOG00000017659
NP_001101936.1 GeneProduct ensembl:ENSRNOG00000038622
Gpx3 GeneProduct ensembl:ENSRNOG00000021809
Cyp1b1 GeneProduct ensembl:ENSRNOG00000040287
GLYATL2 GeneProduct None
Gsto1 GeneProduct ensembl:ENSRNOG00000028746
Cyp20a1 GeneProduct ensembl:ENSRNOG00000017631
LOC687052 GeneProduct ensembl:ENSRNOG00000020743
Ste GeneProduct ensembl:ENSRNOG00000001957
Cyp19a1 GeneProduct ensembl:ENSRNOG00000000196
Cyp21a1 GeneProduct ncbigene:24298
Akr7a3 GeneProduct ensembl:ENSRNOG00000017899
Cyp26c1_predicted GeneProduct ensembl:ENSRNOG00000030698
SULT2A1 GeneProduct ncbigene:24912
LOC683774 GeneProduct ensembl:ENSRNOG00000030880
CYP27B1 GeneProduct ncbigene:114700
Cyp26b1 GeneProduct ensembl:ENSRNOG00000015076
Gstt1 GeneProduct ensembl:ENSRNOG00000001242
Akr1a1 GeneProduct ensembl:ENSRNOG00000016727
Fmo1 GeneProduct ensembl:ENSRNOG00000034191
UGT2B7 GeneProduct None
NP_001102065.1 GeneProduct ensembl:ENSRNOG00000010523
UGT2A2 GeneProduct None
NP_001102492.1 GeneProduct ensembl:ENSRNOG00000011250
NP_001100289.1 GeneProduct ensembl:ENSRNOG00000005930
Gstm3 GeneProduct ensembl:ENSRNOG00000018937
AKR1C3 GeneProduct None
Aldo-keto reductase GeneProduct None
Methyltransferase GeneProduct None
Cyp2w1_predicted GeneProduct ensembl:ENSRNOG00000022355
NP_001101226.1 GeneProduct ensembl:ENSRNOG00000008663
CHSTB_RAT GeneProduct ensembl:ENSRNOG00000008885
Chst9 GeneProduct ncbigene:291770
Sult1c1 GeneProduct ensembl:ENSRNOG00000011269
NP_001102534.1 GeneProduct ensembl:ENSRNOG00000001375
CYP3A7 GeneProduct None
UGT2B15 GeneProduct None
UGT2B11 GeneProduct None
Cyp7a1 GeneProduct ensembl:ENSRNOG00000009488
GSTZ1 GeneProduct ncbigene:681913
Substrate-O-R Metabolite None
CYP4F2 GeneProduct None
Chst2_predicted GeneProduct ensembl:ENSRNOG00000037453
Cyp2f2 GeneProduct ensembl:ENSRNOG00000032805
GAL3ST1 GeneProduct None
NP_001099862.1 GeneProduct ensembl:ENSRNOG00000000605
Gstk1 GeneProduct ensembl:ENSRNOG00000016484
MGC105600 GeneProduct ensembl:ENSRNOG00000028743
Hs2st1 GeneProduct ensembl:ENSRNOG00000012549
Cyp8b1 GeneProduct ensembl:ENSRNOG00000019481
Cyp1a1 GeneProduct ensembl:ENSRNOG00000019500
Glucuronosyltransferase GeneProduct None
Gsr GeneProduct ensembl:ENSRNOG00000014915
Substrate-Ac Metabolite None
SULT4A1 GeneProduct ncbigene:58953
Substrate-OH Metabolite None
HS6ST3 GeneProduct ncbigene:364476
CYP11B2 GeneProduct ncbigene:24294
GSTM5 GeneProduct ncbigene:64352
CYP4Z1 GeneProduct None
Substrate-Gl Metabolite None
AKR1C4 GeneProduct None
Ugt2a1 GeneProduct ensembl:ENSRNOG00000001973
Ndst1 GeneProduct ensembl:ENSRNOG00000019014
AKR1C1 GeneProduct ncbigene:307092
Kcnab1 GeneProduct ensembl:ENSRNOG00000010422
NP_001101195.1 GeneProduct ensembl:ENSRNOG00000011669
RGD1562825_predicted GeneProduct ensembl:ENSRNOG00000025930
Cyp7b1 GeneProduct ensembl:ENSRNOG00000009730
Cyp11a1 GeneProduct ensembl:ENSRNOG00000008074
CYP2C8 GeneProduct None
Ugt2a3_predicted GeneProduct ensembl:ENSRNOG00000001975
Chst10 GeneProduct ensembl:ENSRNOG00000012815
SULT1C1 GeneProduct None
Ephx1 GeneProduct ensembl:ENSRNOG00000003515
Nat9_predicted GeneProduct ensembl:ENSRNOG00000003264
Nat8l_predicted GeneProduct ensembl:ENSRNOG00000015466
Sult1a1 GeneProduct ensembl:ENSRNOG00000019342
NP_001099351.1 GeneProduct ensembl:ENSRNOG00000039017
Hs3st4 GeneProduct ensembl:ENSRNOG00000036723
Ugt1a6 GeneProduct ncbigene:113992
LOC690611 GeneProduct ensembl:ENSRNOG00000013604
NP_001101969.1 GeneProduct ensembl:ENSRNOG00000011367
HS3ST3B1 GeneProduct ncbigene:303218
ST2B1_RAT GeneProduct ensembl:ENSRNOG00000021046
Gss GeneProduct ensembl:ENSRNOG00000018964
Gpx5 GeneProduct ensembl:ENSRNOG00000018596
Substrate-SO3H Metabolite None
Glutathione transferase GeneProduct None
CYP4F8 GeneProduct None
Ephx2 GeneProduct ensembl:ENSRNOG00000017286
NP_001100901.1 GeneProduct ensembl:ENSRNOG00000021521
UGT2B28 GeneProduct None
CYP3A4 GeneProduct None
GSTM1 GeneProduct ncbigene:24423
Kcnab3 GeneProduct ensembl:ENSRNOG00000008480
Fmo2 GeneProduct ensembl:ENSRNOG00000003510
GSTA3 GeneProduct ncbigene:24421
Kcnab2 GeneProduct ensembl:ENSRNOG00000011550
NP_001101988.1 GeneProduct ensembl:ENSRNOG00000021179
Fmo4 GeneProduct ensembl:ENSRNOG00000003400
Cyp26a1 GeneProduct ensembl:ENSRNOG00000016750
Sult1a1 GeneProduct ensembl:ENSRNOG00000019342
Cyp2e1 GeneProduct ensembl:ENSRNOG00000012458
Chst14 GeneProduct ncbigene:691394
Gm766 GeneProduct ensembl:ENSRNOG00000036959
LOC681900 GeneProduct ensembl:ENSRNOG00000014672
Cyp17a1 GeneProduct ensembl:ENSRNOG00000020035
NP_001100897.1 GeneProduct ensembl:ENSRNOG00000016953
Mgst1 GeneProduct ensembl:ENSRNOG00000007743
UGT2B17 GeneProduct ncbigene:286954
Sult1a1 GeneProduct ensembl:ENSRNOG00000019342
AKR1B10 GeneProduct ncbigene:296972
NAT8 GeneProduct ncbigene:64570
CYP3A43 GeneProduct None
Sult1a1 GeneProduct ensembl:ENSRNOG00000019342
Ugt1a3 GeneProduct ensembl:ENSRNOG00000018740
CYP3A5 GeneProduct None
GSTA2 GeneProduct ncbigene:24422
Gstp2 GeneProduct ensembl:ENSRNOG00000018237
Comt GeneProduct ensembl:ENSRNOG00000001889
NP_001100901.1 GeneProduct ensembl:ENSRNOG00000021521
Substrate-SG Metabolite None
Xenobiotic substrate Metabolite None
Ugt1a2 GeneProduct ncbigene:396527
CYP2J2 GeneProduct None
MGST3 GeneProduct ncbigene:289197
Akr1d1 GeneProduct ensembl:ENSRNOG00000013004
Gsto2 GeneProduct ensembl:ENSRNOG00000012801
Gstm5 GeneProduct ensembl:ENSRNOG00000018732
LOC685402 GeneProduct ensembl:ENSRNOG00000022982
Gstt2 GeneProduct ensembl:ENSRNOG00000028188
NP_001100974.1 GeneProduct ensembl:ENSRNOG00000022919
CYP2A13 GeneProduct None
Cyp51 GeneProduct ensembl:ENSRNOG00000007234
CHST12 GeneProduct ncbigene:304322

References