Fatty acid beta-oxidation (WP143)

Complete fatty acid beta-oxidation pathway for saturated and unsaturated fatty acids. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP143 CPTAC Assay Portal]
last edited

Authors

Michiel, Evelo, MaintBot, Susan, Pahles, FerryJagers, AdrienDefay, AlexanderPico, Egonw, Mkutmon, DeSl, Priyanka K, Khanspers, Licong, and Eweitz

Cited In

Organism

Homo sapiens

Communities

CPTAC Lipids and LIPID MAPS

Annotations

Disease Ontology: lipid metabolism disorder

Pathway Ontology: fatty acid degradation pathway fatty acid metabolic pathway fatty acid beta degradation pathway

Participants

Label Type Compact Identifier
Cronoyl-CoA Metabolite None
trans,cis-Lauro-2,6-dienoyl-CoA Metabolite chebi:28387
3-Oxocanoyl-CoA Metabolite None
3-Oxododexanoyl-CoA Metabolite pubchem.compound:11966169
(S)-Hydrocyhexanoyl Metabolite None
Fatty Acid Metabolite chebi:35366
4-cis-dexeboyl-CoA Metabolite None
Octaoyl-CoA Metabolite None
(S)-3-Hydroxydodexanonyl-CoA Metabolite None
Trans-Tetradex-2-enoyl-CoA Metabolite None
Glutarate Metabolite pubchem.compound:743
Trans-Hexadecanoyl-CoA Metabolite None
Dxotetradecanoyl-CoA Metabolite None
HADHA GeneProduct ncbigene:3030
Trans-Oct-2-enoyl-CoA Metabolite chebi:27537
Myristoyl-CoA Metabolite chebi:15532
(S)-3-Hydroxytetradecanoyl-CoA Metabolite chebi:27466
Acetyl-CoA Metabolite cas:72-89-9
Acetyl-CoA Metabolite cas:72-89-9
ACADM GeneProduct ncbigene:34
HADHB GeneProduct ncbigene:3032
PNPLA2 GeneProduct ncbigene:57104
Glutaryl-CoA Metabolite chebi:15524
CPT2 GeneProduct ncbigene:1376
Glyceraldehyde-3-Phosphate Metabolite cas:591-57-1
2-trans-dodecenoyl-CoA Metabolite chebi:15471
ACADS GeneProduct ncbigene:35
ACADM GeneProduct ncbigene:34
HADHB GeneProduct ncbigene:3032
Glycerol Metabolite cas:56-81-5
cis,cis-3,6-Dodecadienoyl-CoA Metabolite chebi:28002
DCI GeneProduct ncbigene:1632
ECHS1 GeneProduct ncbigene:1892
GCDH GeneProduct ncbigene:2639
HADHB GeneProduct ncbigene:3032
Trans-Dec-2-enoyl-CoA Metabolite chebi:10723
HADHB GeneProduct ncbigene:3032
HADHSC GeneProduct ncbigene:3033
HADHB GeneProduct ncbigene:3032
HADHB GeneProduct ncbigene:3032
HADHB GeneProduct ncbigene:3032
3-Oxo-octanoyl-CoA Metabolite chebi:28264
ACADVL GeneProduct ncbigene:37
Acetyl-CoA Metabolite cas:72-89-9
HADHB GeneProduct ncbigene:3032
HADHB GeneProduct ncbigene:3032
3-Oxohexanoyl-CoA Metabolite chebi:27648
GPD2 GeneProduct ncbigene:2820
2-trans-4-cis-decadienoyl-CoA Metabolite chebi:29119
Butanoyl-CoA Metabolite chebi:15517
HADHA GeneProduct ncbigene:3030
HADHSC GeneProduct ncbigene:3033
HADHA GeneProduct ncbigene:3030
Acetyl-CoA Metabolite cas:72-89-9
Acetyl-CoA Metabolite cas:72-89-9
Decanoyl-CoA Metabolite chebi:28493
Linoleoyl-CoA Metabolite cas:40757-80-0
3-Oxopalmitoyl-CoA Metabolite chebi:15491
ACSL5 GeneProduct ncbigene:51703
DLD GeneProduct ncbigene:1738
HADHA GeneProduct ncbigene:3030
ACAS2 GeneProduct ncbigene:55902
HADHSC GeneProduct ncbigene:3033
TPI1 GeneProduct ncbigene:7167
GK2 GeneProduct ncbigene:2712
HADHB GeneProduct ncbigene:3032
Dihydroxyacetone Phosphate Metabolite cas:57-04-5
ECHS1 GeneProduct ncbigene:1892
ACSL1 GeneProduct ncbigene:2180
DECR1 GeneProduct ncbigene:1666
Trans-Hex-2-enoyl-CoA Metabolite chebi:28706
LIPC GeneProduct ncbigene:3990
(S)-3-Hydroxyhexadecanoyl-CoA Metabolite chebi:27402
SLC25A20 GeneProduct ncbigene:788
ACADL GeneProduct ncbigene:33
ACADL GeneProduct ncbigene:33
CRAT GeneProduct ncbigene:1384
(S)-3-Hydroxybutanoyl-CoA Metabolite chebi:15453
LIPE GeneProduct ncbigene:3991
ECHS1 GeneProduct ncbigene:1892
Lauroyl-CoA Metabolite cas:6244-92-4
ACSL6 GeneProduct ncbigene:23305
DCI GeneProduct ncbigene:1632
Hexanoyl-CoA Metabolite chebi:27540
HADHSC GeneProduct ncbigene:3033
L-Glycerol-3-Phosphate Metabolite chebi:15978
HADHB GeneProduct ncbigene:3032
CPT1A GeneProduct ncbigene:1374
TCA cycle Pathway wikipathways:WP78
CPT1B GeneProduct ncbigene:1375
HADHA GeneProduct ncbigene:3030
HADHA GeneProduct ncbigene:3030
HADHA GeneProduct ncbigene:3030
Acyl-CoA Metabolite cas:9029-97-4
HADHSC GeneProduct ncbigene:3033
ECHS1 GeneProduct ncbigene:1892
HADHA GeneProduct ncbigene:3030
HADHB GeneProduct ncbigene:3032
ACSL4 GeneProduct ncbigene:2182
(S)-3-Hydroxydecanoyl-CoA Metabolite chebi:28325
ACADS GeneProduct ncbigene:35
GK GeneProduct ncbigene:2710
LIPF GeneProduct ncbigene:8513
(S)-3-Hydroxyoctanoyl-CoA Metabolite chebi:28632
HADHA GeneProduct ncbigene:3030
Acetyl-CoA Metabolite cas:72-89-9
Palmitoyl-CoA Metabolite chebi:15525
ACADL GeneProduct ncbigene:33
HADHB GeneProduct ncbigene:3032
HADHA GeneProduct ncbigene:3030
HADHA GeneProduct ncbigene:3030
Acetoacetyl-CoA Metabolite cas:1420-36-6
CHKB GeneProduct ncbigene:1120
Acetyl-CoA Metabolite cas:72-89-9
ECHS1 GeneProduct ncbigene:1892
Acetyl-CoA Metabolite cas:72-89-9
HADHA GeneProduct ncbigene:3030
ACAT1 GeneProduct ncbigene:38
ACSL3 GeneProduct ncbigene:2181
3-trans-decenoyl-CoA Metabolite chebi:29126
Triacylglycerol Metabolite chebi:17855
HADHA GeneProduct ncbigene:3030
ACADL GeneProduct ncbigene:33
LPL GeneProduct ncbigene:4023
Acetyl-CoA Metabolite cas:72-89-9
ACADM GeneProduct ncbigene:34
TCA cycle Pathway wikipathways:WP78
TCA cycle Pathway wikipathways:WP78
TCA cycle Pathway wikipathways:WP78
TCA cycle Pathway wikipathways:WP78
TCA cycle Pathway wikipathways:WP78
TCA cycle Pathway wikipathways:WP78
TCA cycle Pathway wikipathways:WP78

References