miRNAs involved in DNA damage response (WP1545)

MicroRNA clusters involved in de DNA damage response. Genes they regulated and genes that regulate them. All genes presented in this pathway can also be found in the pathway "DNA damage response(Homo sapiens)". More info can be found there. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP1545 CPTAC Assay Portal].
last edited


J.krumeich, Khanspers, MaintBot, MartijnVanIersel, Andra, Mkutmon, Egonw, and Susan

Cited In


Homo sapiens



Pathway Ontology: DNA repair pathway microRNA pathway


Label Type Compact Identifier
hsa-mir-18a GeneProduct ensembl:ENSG00000283815
hsa-miR-223 gene GeneProduct None
hsa-miR-29b-2/29c cluster GeneProduct None
hsa-miR-106b/25 cluster GeneProduct None
hsa-mir-15b/16-2 cluster GeneProduct None
hsa-mir-371 GeneProduct ensembl:ENSG00000199031
E2F1 GeneProduct ncbigene:1869
c-Myc GeneProduct ncbigene:4609
hsa-let-7f GeneProduct ensembl:ENSG00000199072
hsa-miR-222/221 cluster GeneProduct None
ATM GeneProduct ncbigene:472
hsa-mir-542 GeneProduct ensembl:ENSG00000207784
hsa-mir-449c GeneProduct mirbase:MI0003823
hsa-mir-181a-2/181b-2 cluster GeneProduct None
hsa-let-7d GeneProduct ensembl:ENSG00000199133
hsa-mir-106b GeneProduct ensembl:ENSG00000208036
hsa-mir-3074 GeneProduct mirbase:MI0014181
c-Myc GeneProduct ncbigene:4609
hsa-mir-372 GeneProduct ensembl:ENSG00000199095
hsa-mir-424 GeneProduct ensembl:ENSG00000284231
hsa-mir-223 GeneProduct ensembl:ENSG00000284567
hsa-mir-29b-1 GeneProduct ensembl:ENSG00000283797
hsa-mir-210 GeneProduct ensembl:ENSG00000199038
hsa-miR-29b-1/29a cluster GeneProduct None
hsa-mir-24 GeneProduct ensembl:ENSG00000207617
hsa-miR-203 gene GeneProduct None
hsa-miR-330 gene GeneProduct None
hsa-mir-374b GeneProduct ensembl:ENSG00000212027
hsa-mir-450b GeneProduct ensembl:ENSG00000216001
ABL1 GeneProduct ncbigene:25
CDK6 GeneProduct ncbigene:1021
hsa-mir-27b GeneProduct ensembl:ENSG00000207864
CDKN1A GeneProduct ncbigene:1026
hsa-mir-15a/16-1 cluster GeneProduct None
hsa-mir-143 GeneProduct ensembl:ENSG00000284182
hsa-mir-34b/34c cluster GeneProduct None
hsa-miR-424/450b cluster GeneProduct None
CCND1 GeneProduct ncbigene:595
hsa-mir-29c GeneProduct ensembl:ENSG00000284214
hsa-mir-23a GeneProduct ensembl:ENSG00000207980
hsa-mir-15a GeneProduct ensembl:ENSG00000283785
CCNE1 GeneProduct ncbigene:898
hsa-mir-503 GeneProduct ensembl:ENSG00000208005
hsa-mir-143/145 cluster GeneProduct None
hsa-mir-195 GeneProduct ensembl:ENSG00000284112
hsa-let-7a-1/7d cluster GeneProduct None
hsa-mir-450a GeneProduct ensembl:ENSG00000207755
hsa-let-7a GeneProduct ensembl:ENSG00000199165
hsa-mir-16 GeneProduct ensembl:ENSG00000208006
hsa-mir-21 GeneProduct ensembl:ENSG00000284190
hsa-mir-25 GeneProduct ensembl:ENSG00000207547
hsa-mir-181a-1/181b-1 cluster GeneProduct None
hsa-mir-374b/421 cluster GeneProduct None
CDKN1B GeneProduct ncbigene:1027
hsa-mir-221 GeneProduct ensembl:ENSG00000207870
hsa-mir-19a GeneProduct ensembl:ENSG00000284204
hsa-mir-181a GeneProduct ensembl:ENSG00000207759
H2AFX GeneProduct ncbigene:3014
hsa-miR-449c/449a cluster GeneProduct None
hsa-let-7a-3/7b cluster GeneProduct None
hsa-mir-93 GeneProduct ensembl:ENSG00000207757
hsa-mir-29a GeneProduct ensembl:ENSG00000284032
CCND3 GeneProduct ncbigene:896
hsa-mir-181b GeneProduct ensembl:ENSG00000207975
hsa-miR-17/92a-1 cluster GeneProduct None
hsa-mir-100 GeneProduct ensembl:ENSG00000207994
hsa-mir-203 GeneProduct ensembl:ENSG00000207568
hsa-mir-145 GeneProduct ensembl:ENSG00000276365
hsa-mir-34b GeneProduct ensembl:ENSG00000207811
hsa-mir-19b-1 GeneProduct ensembl:ENSG00000284375
CREB1 GeneProduct ncbigene:1385
hsa-let-7b GeneProduct ensembl:ENSG00000284520
hsa-mir-23b/24-1 cluster GeneProduct None
hsa-mir-373 GeneProduct ensembl:ENSG00000199143
hsa-miR-21gene GeneProduct None
hsa-mir-34c GeneProduct ensembl:ENSG00000207562
hsa-miR-195/497 cluster GeneProduct None
hsa-mir-497 GeneProduct ensembl:ENSG00000284027
CDC25A2 GeneProduct ncbigene:993
hsa-mir-222 GeneProduct ensembl:ENSG00000207725
hsa-mir-23a/24-2 cluster GeneProduct None
hsa-mir-421 GeneProduct ensembl:ENSG00000202566
hsa-mir-23b GeneProduct ensembl:ENSG00000207563
CCND1 GeneProduct ncbigene:595
hsa-mir-449a GeneProduct ensembl:ENSG00000198983
hsa-mir-371/373 cluster GeneProduct None
TP53 GeneProduct ncbigene:7157
hsa-mir-27a GeneProduct ensembl:ENSG00000207808
hsa-mir-15b GeneProduct ensembl:ENSG00000207779
hsa-mir-17 GeneProduct ensembl:ENSG00000284536
hsa-mir-20a GeneProduct ensembl:ENSG00000283762
hsa-mir-92a-1 GeneProduct ensembl:ENSG00000283705
E2F1 GeneProduct ncbigene:1869
hsa-mir-449b GeneProduct ensembl:ENSG00000207728
hsa-miR-210 gene GeneProduct None
hsa-let-7a-2/100 cluster GeneProduct None
RAD52 GeneProduct ncbigene:5893
hsa-mir-330 GeneProduct ensembl:ENSG00000284544


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