Transcription factors regulate miRNAs related to cardiac hypertrophy (WP1559)

Transcription Factors that possibly regulate the expression of microRNAs related to cardiac hypertrophy. Interactions found by using TransMir. MicroRNAs are represented by a purple color and a rounded rectangle. Proteins on this pathway have targeted assays available via the [ CPTAC Assay Portal].
last edited


MLevels, Khanspers, MaintBot, AMTan, Egonw, Marvin M2, and Eweitz

Cited In


Homo sapiens



Pathway Ontology: hypertrophic cardiomyopathy pathway

Cell Type Ontology: cardiac muscle cell


Label Type Compact Identifier
hsa-mir-21 Rna ensembl:ENSG00000284190
hsa-mir-125b-2 Rna ensembl:ENSG00000207863
NFkB GeneProduct ncbigene:4790
hsa-mir-125b-1 Rna ensembl:ENSG00000207971
NFkB GeneProduct ncbigene:4790
RAS GeneProduct ncbigene:5923
MIR1-2 Rna ensembl:ENSG00000284453
AKT1 GeneProduct ncbigene:207
Calcineurin GeneProduct ncbigene:5534
hsa-mir-133b Rna ensembl:ENSG00000199080
AKT1 GeneProduct ncbigene:207
MIR29A GeneProduct ensembl:ENSG00000284032
hsa-mir-1-1 Rna ensembl:ENSG00000199017
TGFbeta GeneProduct ncbigene:7040
MEF-2 GeneProduct ncbigene:50804
AKT2 GeneProduct ncbigene:208
STAT3 GeneProduct ncbigene:6774