Splicing factor NOVA regulated synaptic proteins (WP1983)

Synaptic Communication influenced by NOVA-splicing regulation
last edited

Authors

B.taneri, Mkutmon, MaintBot, and Ddigles

Cited In

Organism

Mus musculus

Communities

Annotations

Pathway Ontology: cadherin mediated signaling pathway

Participants

Label Type Compact Identifier
Cav2.2 GeneProduct ensembl:ENSMUSG00000000058
4.1G GeneProduct ncbigene:13822
NIK/Mapk4 GeneProduct ensembl:ENSMUSG00000024558
N-Cadherin GeneProduct ncbigene:12558
LAR GeneProduct None
SKIP GeneProduct ncbigene:66354
MAP4 Protein uniprot:P27546
AGRIN Protein uniprot:A2ASQ1
Calsyntenin GeneProduct ncbigene:65945
EphrinA5R GeneProduct None
GIRK2 GeneProduct ncbigene:16522
PIP2 Metabolite hmdb:HMDB0010032
Clasp1 GeneProduct ensembl:ENSMUSG00000064302
Slo GeneProduct ncbigene:16531
CASK GeneProduct ensembl:ENSMUSG00000031012
neurochondrin GeneProduct ncbigene:26562
GlyRa2 GeneProduct None
GABAARg2 GeneProduct ncbigene:14406
JNK2 GeneProduct ncbigene:26420
PMCA1 GeneProduct ncbigene:67972
Syntaxin1 GeneProduct None
Plcb4 GeneProduct ensembl:ENSMUSG00000039943
Rap1gap GeneProduct ncbigene:110351
Syntaxin 2 GeneProduct ncbigene:13852
Camk2g GeneProduct ensembl:ENSMUSG00000021820
a-catenin GeneProduct None
Igsf4a GeneProduct ncbigene:54725
Neogenin GeneProduct ncbigene:18007
nAChRa2 GeneProduct None
Cav2.2 GeneProduct ensembl:ENSMUSG00000000058
Cask GeneProduct ensembl:ENSMUSG00000031012
Gephrin GeneProduct ncbigene:268566
CASK Protein uniprot:P06796
Dab1 GeneProduct ensembl:ENSMUSG00000028519
Aplp2 GeneProduct ensembl:ENSMUSG00000031996
Kcnq2 GeneProduct ensembl:ENSMUSG00000016346
Munc18 GeneProduct ncbigene:20911
4.1R GeneProduct ncbigene:269587
4.1B GeneProduct ncbigene:13823
Chl1 GeneProduct ensembl:ENSMUSG00000030077
Netrin G1 GeneProduct ncbigene:80883
Rap1 GeneProduct ncbigene:57321
EphrinA5 GeneProduct ncbigene:13640
NMDAR2B GeneProduct ncbigene:14812
NMDAR1 GeneProduct ncbigene:14810
Chl1 GeneProduct ensembl:ENSMUSG00000030077
N-Cadherin GeneProduct ncbigene:12558
Ankyrin G GeneProduct ncbigene:11735
CASK GeneProduct ensembl:ENSMUSG00000031012
Dab1 GeneProduct ensembl:ENSMUSG00000028519
a-catenin GeneProduct None
LAR GeneProduct None
GluR6 GeneProduct ncbigene:14806
Cask GeneProduct ensembl:ENSMUSG00000031012
PKCz GeneProduct ncbigene:18762
GABAB2R GeneProduct ncbigene:242425
nAChRa4 GeneProduct None
Plcb4 GeneProduct ensembl:ENSMUSG00000039943
PIP2 Metabolite hmdb:HMDB0010032
Ankyrin G GeneProduct ncbigene:11735
Ankyrin G GeneProduct ncbigene:11735
JNK2 GeneProduct ncbigene:26420
4.1R GeneProduct ncbigene:269587
4.1R GeneProduct ncbigene:269587
GluR6 GeneProduct ncbigene:14806
Slo GeneProduct ncbigene:16531
PKCz GeneProduct ncbigene:18762
GABAB2R GeneProduct ncbigene:242425
Gephrin GeneProduct ncbigene:268566
Plcb4 GeneProduct ensembl:ENSMUSG00000039943
4.1N GeneProduct ncbigene:13821
Igsf4b GeneProduct ncbigene:94332
Integrin a2 GeneProduct None
validated target Unknown None
CLIP predicted target Unknown None
validated target - predicted by bioinformatics Unknown None
validated target - predicted by splicing microarray Unknown None
validated target - predicted by CLIP Unknown None

References

  1. Ule J, Ule A, Spencer J, Williams A, Hu J-S, Cline M, et al. Nova regulates brain-specific splicing to shape the synapse. Nat Genet. 2005 Aug;37(8):844–52. PubMed Europe PMC Scholia
  2. Ule J, Stefani G, Mele A, Ruggiu M, Wang X, Taneri B, et al. An RNA map predicting Nova-dependent splicing regulation. Nature. 2006 Nov 30;444(7119):580–6. PubMed Europe PMC Scholia