SREBF and miR33 in cholesterol and lipid homeostasis (WP2011)

This pathway describes transcription factor-microRNA circuits governing cholesterol and lipid homeostasis. It is based on a seminar by Dr. Anders Näär. Proteins on this pathway have targeted assays available via the [ CPTAC Assay Portal]
last edited


Samuel Sklar, Khanspers, MaintBot, Lindarieswijk, Mkutmon, and Finterly

Cited In


Homo sapiens



Pathway Ontology: homeostasis pathway


Label Type Compact Identifier
SREBF1 GeneProduct ensembl:ENSG00000072310
PPARGC1A GeneProduct ensembl:ENSG00000109819
FASN GeneProduct ncbigene:2194
SIRT6 GeneProduct ensembl:ENSG00000077463
HMGCR GeneProduct ensembl:ENSG00000113161
SIRT1 GeneProduct ensembl:ENSG00000096717
MTOR GeneProduct ensembl:ENSG00000198793
SCD GeneProduct ncbigene:6319
NR1H3 GeneProduct ensembl:ENSG00000025434
PPARA GeneProduct ensembl:ENSG00000186951
MIR33A Rna ensembl:ENSG00000207932
MED15 GeneProduct ensembl:ENSG00000099917
SREBF2 GeneProduct ensembl:ENSG00000198911
MIR33B Rna ensembl:ENSG00000207839
HMGCS1 GeneProduct ensembl:ENSG00000112972
LDLR GeneProduct ensembl:ENSG00000130164
ABCA1 GeneProduct ncbigene:19
PRKAA1 GeneProduct ncbigene:5562


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