Drug induction of bile acid pathway (WP2289)

Several drug (e.g. chlozapine) and their inhibitory effects on targets of the bile acid production pathway.
last edited

Authors

Riannefijten, MaintBot, Egonw, Susan, Mkutmon, Roelod, and Eweitz

Cited In

Organism

Homo sapiens

Communities

Annotations

Pathway Ontology: drug pathway bile acid signaling pathway

Participants

Label Type Compact Identifier
SLCO1B1 GeneProduct ncbigene:10599
SULT2A1 GeneProduct ncbigene:6822
Chlorpromazine Metabolite pubchem.compound:2726
Bile Acids Metabolite chebi:3098
Ezetimibe Metabolite pubchem.compound:150311
CYP3A4 GeneProduct ncbigene:1576
Troglitazone Metabolite pubchem.compound:5591
SLC10A1 GeneProduct ncbigene:6554
CYP7A1 GeneProduct ncbigene:1581
Cholesterol Metabolite hmdb:HMDB0000067
BA-R Metabolite None
Tetrahydrocortisone Metabolite hmdb:HMDB0000903
BAAT GeneProduct ncbigene:570
ABCB1 GeneProduct ncbigene:5243
Cyclosporin Metabolite pubchem.compound:5284373
Glycocholic acid Metabolite hmdb:HMDB0000138
NR1H4 GeneProduct ncbigene:9971
OSTalpha GeneProduct ncbigene:200931
Clozapine Metabolite pubchem.compound:135398737
Taurocholic acid Metabolite hmdb:HMDB0000036
Bilirubin Metabolite hmdb:HMDB0000054
Isoursodeoxycholic acid Metabolite hmdb:HMDB0000686
Deoxycholic acid Metabolite hmdb:HMDB0000626
VDR GeneProduct ncbigene:7421
NR1I3 GeneProduct ncbigene:9970
NR1I2 GeneProduct ncbigene:8856
Methylprednisolone Metabolite pubchem.compound:6741
Cimetidine Metabolite pubchem.compound:2756
OSTBETA GeneProduct ncbigene:123264
ABCC4 GeneProduct ncbigene:10257
ABCB11 GeneProduct ncbigene:8647
ABCC3 GeneProduct ncbigene:8714
ABCC2 GeneProduct ncbigene:1244
Phospholipids Metabolite chebi:16247
Digoxin Metabolite hmdb:HMDB0001917
Clarithromyci Metabolite pubchem.compound:84029
Erythromycin Metabolite pubchem.compound:12560
Silybin Metabolite pubchem.compound:31553
Glyburide Metabolite pubchem.compound:3488
Tacrolimus Metabolite pubchem.compound:445643
Trabectedin Metabolite pubchem.compound:108150
Phomin Metabolite pubchem.compound:5311281
Colchicine Metabolite pubchem.compound:6167
Ranitidine Metabolite hmdb:HMDB0001930
Oxiglutatione Metabolite pubchem.compound:65359

References