Deregulation of Rab and Rab effector genes in bladder cancer (WP2291)

Example of the Rab27 cluster. The Rab27 cluster is comprised of the two RAB27 isoforms (RAB27A and RAB27B), the GEF MADD, the GAP TBC1D10A and 12 effector proteins
last edited


Anwesha, MaintBot, Christine Chichester, Egonw, Fehrhart, and Eweitz

Cited In


Homo sapiens




Pathway Ontology: urinary bladder cancer pathway cancer pathway

Disease Ontology: urinary bladder cancer


Label Type Compact Identifier
MADD GeneProduct ensembl:ENSG00000110514
MLPH GeneProduct ensembl:ENSG00000115648
MYRIP GeneProduct ensembl:ENSG00000170011
RPH3A GeneProduct ensembl:ENSG00000089169
RPH3AL GeneProduct ensembl:ENSG00000181031
SYTL1 GeneProduct ensembl:ENSG00000142765
UNC13D GeneProduct ensembl:ENSG00000092929
SYTL2 GeneProduct ensembl:ENSG00000137501
EXPH5 GeneProduct ensembl:ENSG00000110723
SYTL3 GeneProduct ensembl:ENSG00000164674
SYTL4 GeneProduct ensembl:ENSG00000102362
SYTL5 GeneProduct ensembl:ENSG00000147041
TBC1D10A GeneProduct ensembl:ENSG00000099992
RAB27A GeneProduct ensembl:ENSG00000069974
RAB27B GeneProduct ensembl:ENSG00000041353
GCC2 GeneProduct ensembl:ENSG00000135968


  1. Ho JR, Chapeaublanc E, Kirkwood L, Nicolle R, Benhamou S, Lebret T, et al. Deregulation of Rab and Rab effector genes in bladder cancer. PLoS One. 2012;7(6):e39469. PubMed Europe PMC Scholia