IL-3 signaling pathway (WP319)

Interleukin-3 belongs to a family of cytokines, which includes IL-5 and GM-CSF. It signals through a receptor complex comprising of an IL-3 specific IL-3 receptor alpha subunit (IL3RA) and a common beta chain, which is shared between all members of this cytokine family. Binding of IL-3 to IL3RA recruits the beta chain to the complex, which activates the JAK/STAT, MAPK and PI 3-kinase signaling modules. Source: NetPath
last edited


A.Pandey, MaintBot, Christine Chichester, and Eweitz

Cited In


Rattus norvegicus



Pathway Ontology: interleukin-3 signaling pathway


Label Type Compact Identifier
IL3 GeneProduct ncbigene:24495
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Ywhaz GeneProduct ncbigene:25578
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Matk GeneProduct ncbigene:60450
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Pik3cd GeneProduct ncbigene:366508
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Bmx GeneProduct ncbigene:367786
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Dnm1 GeneProduct ncbigene:140694
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Gene Symbol GeneProduct None
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