Hfe effect on hepcidin production (WP3924)

new pathway, converted from mouse WP3673
last edited

Authors

Khanspers and AlexanderPico

Cited In

Organism

Homo sapiens

Communities

Annotations

Pathway Ontology: regulatory pathway iron homeostasis pathway iron homeostasis pathway regulatory pathway

Participants

Label Type Compact Identifier
HFE GeneProduct ensembl:ENSG00000010704
TMPRSS6 GeneProduct ensembl:ENSG00000187045
HFE2 GeneProduct ensembl:ENSG00000168509
HAMP GeneProduct ensembl:ENSG00000105697
BMP6 GeneProduct ensembl:ENSG00000153162
SMAD7 GeneProduct ensembl:ENSG00000101665
ID1 GeneProduct ensembl:ENSG00000125968
HFE GeneProduct ensembl:ENSG00000010704
HFE GeneProduct ensembl:ENSG00000010704

References

  1. Finberg KE, Whittlesey RL, Andrews NC. Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice. Blood. 2011 Apr 28;117(17):4590–9. PubMed Europe PMC Scholia