Oxidative damage response (WP3941)

This pathway shows how tissue is damaged when oxygen levels are not balanced and become too high. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP3941 CPTAC Assay Portal]
last edited

Authors

Khanspers and Eweitz

Cited In

Organism

Homo sapiens

Communities

Annotations

Pathway Ontology: oxidative stress response pathway oxidative stress response pathway

Participants

Label Type Compact Identifier
PCNA GeneProduct ensembl:ENSG00000132646
C1QC GeneProduct ensembl:ENSG00000159189
CDKN1C GeneProduct ensembl:ENSG00000129757
C1QB GeneProduct ensembl:ENSG00000173369
C5AR1 GeneProduct ensembl:ENSG00000197405
TNFRSF1B GeneProduct ensembl:ENSG00000028137
C5 GeneProduct ensembl:ENSG00000106804
TRAF3 GeneProduct ensembl:ENSG00000131323
BCL2 GeneProduct ensembl:ENSG00000171791
CR2 GeneProduct ensembl:ENSG00000117322
Oxidative stress Pathway wikipathways:WP412
BAD GeneProduct ensembl:ENSG00000002330
APAF1 GeneProduct ensembl:ENSG00000120868
MAP3K9 GeneProduct ensembl:ENSG00000006432
MAPK13 GeneProduct ensembl:ENSG00000156711
CDC42 GeneProduct ensembl:ENSG00000070831
TRAF2 GeneProduct ensembl:ENSG00000127191
C4B GeneProduct ensembl:ENSG00000224389
CDKN1A GeneProduct ensembl:ENSG00000124762
Cyct GeneProduct None
C1S GeneProduct ensembl:ENSG00000182326
C1R GeneProduct ensembl:ENSG00000159403
TDP2 GeneProduct ensembl:ENSG00000111802
CYCS GeneProduct ensembl:ENSG00000172115
TNK2 GeneProduct ensembl:ENSG00000061938
C3AR1 GeneProduct ensembl:ENSG00000171860
DNA Replication Pathway wikipathways:WP150
MAP2K4 GeneProduct ensembl:ENSG00000065559
BAG4 GeneProduct ensembl:ENSG00000156735
C2 GeneProduct ensembl:ENSG00000166278
CDKN1B GeneProduct ensembl:ENSG00000111276
TRAF1 GeneProduct ensembl:ENSG00000056558
NFKBIE GeneProduct ensembl:ENSG00000146232
NFKB1 GeneProduct ensembl:ENSG00000109320
TNF GeneProduct ensembl:ENSG00000232810
GADD45A GeneProduct ensembl:ENSG00000116717
MAP3K1 GeneProduct ensembl:ENSG00000095015
MAPK10 GeneProduct ensembl:ENSG00000109339
TRAF6 GeneProduct ensembl:ENSG00000175104
C1QA GeneProduct ensembl:ENSG00000173372
CASP3 GeneProduct ensembl:ENSG00000164305
Apoptosis Pathway wikipathways:WP1254
BAK1 GeneProduct ensembl:ENSG00000030110
CASP9 GeneProduct ensembl:ENSG00000132906

References