NO/cGMP/PKG mediated neuroprotection (WP4008)

NO/cGMP/PKG mediated Neuroprotection
last edited

Authors

SauerThorben, Egonw, Khanspers, MaintBot, Laurent, and Eweitz

Cited In

Organism

Homo sapiens

Communities

Annotations

Disease Ontology: dementia

Cell Type Ontology: neuron neural cell

Pathway Ontology: signaling pathway signaling pathway involving second messengers

Participants

Label Type Compact Identifier
Ca2+ Metabolite chebi:29108
TSPO GeneProduct ensembl:ENSG00000100300
GRIN2D GeneProduct ensembl:ENSG00000105464
NADP Metabolite chebi:18009
ACTN2 GeneProduct ensembl:ENSG00000077522
CNGB1 GeneProduct ensembl:ENSG00000070729
GUCY1B2 GeneProduct ensembl:ENSG00000123201
XIAP GeneProduct ensembl:ENSG00000101966
PDE3 GeneProduct ensembl:ENSG00000172572
CNGA3 GeneProduct ensembl:ENSG00000144191
GRIN2B GeneProduct ensembl:ENSG00000273079
CNGA2 GeneProduct ensembl:ENSG00000183862
CAMK2G GeneProduct ensembl:ENSG00000148660
O2 Metabolite chebi:29372
GTP Metabolite chebi:37565
L-Arginine Metabolite chebi:16467
IL-1B Protein ensembl:ENSG00000125538
GUCY1A2 GeneProduct ensembl:ENSG00000152402
GUCY1A3 GeneProduct ensembl:ENSG00000164116
eNOS GeneProduct ensembl:ENSG00000164867
CNGA1 GeneProduct ensembl:ENSG00000198515
NPR1 GeneProduct ensembl:ENSG00000169418
NFKB1 GeneProduct ensembl:ENSG00000109320
K+ Metabolite chebi:29103
L-Citrulline Metabolite chebi:16349
CNGB3 GeneProduct ensembl:ENSG00000170289
AKAP9 GeneProduct ensembl:ENSG00000127914
CASP9 GeneProduct ensembl:ENSG00000132906
BCL2 GeneProduct ensembl:ENSG00000171791
Caspase Cascade Pathway None
nNOS GeneProduct ensembl:ENSG00000089250
GUCY1B3 GeneProduct ensembl:ENSG00000061918
NO Metabolite chebi:16480
Ca2+ Metabolite chebi:29108
Apoptosis Pathway wikipathways:WP254
CAMK2B GeneProduct ensembl:ENSG00000058404
ANP GeneProduct ensembl:ENSG00000175206
NEFL GeneProduct ensembl:ENSG00000277586
L-Glutamate Metabolite chebi:16015
PDE2 GeneProduct ensembl:ENSG00000186642
NADPH Metabolite chebi:16474
GRIN2A GeneProduct ensembl:ENSG00000183454
CALM1 GeneProduct ensembl:ENSG00000198668
CAMK2A GeneProduct ensembl:ENSG00000070808
Cytochrome C GeneProduct ensembl:ENSG00000172115
cGMP Metabolite chebi:16356
CAMK2D GeneProduct ensembl:ENSG00000145349
Cyclophilin D GeneProduct ensembl:ENSG00000171497
TNF-a Protein ensembl:ENSG00000232810
GRIN2C GeneProduct ensembl:ENSG00000161509
PKG2 GeneProduct ensembl:ENSG00000138669
GRIN1 GeneProduct ensembl:ENSG00000176884
CNGA4 GeneProduct ensembl:ENSG00000132259
TBH Metabolite chebi:64090
NFKBIA GeneProduct ensembl:ENSG00000100906
IFN-Gamma Protein ensembl:ENSG00000111537
AMP Metabolite chebi:16027
NFKB3 GeneProduct ensembl:ENSG00000173039
CREB1 GeneProduct ensembl:ENSG00000118260
Mg2+ Metabolite chebi:18420
BNP GeneProduct ensembl:ENSG00000120937
DLG4 GeneProduct ensembl:ENSG00000132535
Ca2+ Metabolite chebi:29108
LPS Complex chebi:89981
iNOS GeneProduct ensembl:ENSG00000007171
cAMP Metabolite chebi:17489
O2 Metabolite chebi:29372
L-Arginine Metabolite chebi:16467
NADPH Metabolite chebi:16474
TBH Metabolite chebi:64090
NADP Metabolite chebi:18009
L-Citrulline Metabolite chebi:16349
NO Metabolite chebi:16480
ACTN2 GeneProduct ensembl:ENSG00000077522
DLG4 GeneProduct ensembl:ENSG00000132535
Ca2+ Metabolite chebi:29108
CALM1 GeneProduct ensembl:ENSG00000198668
O2 Metabolite chebi:29372
L-Arginine Metabolite chebi:16467
NADPH Metabolite chebi:16474
TBH Metabolite chebi:64090
NADP Metabolite chebi:18009
L-Citrulline Metabolite chebi:16349
NO Metabolite chebi:16480
NO Metabolite chebi:16480
K+ Metabolite chebi:29103
Ca2+ Metabolite chebi:29108
BAD GeneProduct ensembl:ENSG00000002330
K+ Metabolite chebi:29103
Ca2+ Metabolite chebi:29108
K+ Metabolite chebi:29103
Ca2+ Metabolite chebi:29108
Cytochrome C GeneProduct ensembl:ENSG00000172115

References