Cell cycle and cell division (WP414)

(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle involves processes crucial to the survival of a cell, including the detection and repair of genetic damage as well as the prevention of uncontrolled cell division. Two key classes of regulatory molecules, cyclins and cyclin-dependent kinases (CDKs), determine a cell's progress through the cell cycle.
last edited


Nsalomonis, MaintBot, BruceConklin, MartijnVanIersel, StephanieWiddison, Christine Chichester, Egonw, Mkutmon, Khanspers, AdoBioInfo, and Eweitz

Cited In


Saccharomyces cerevisiae



Pathway Ontology: cell cycle pathway, mitotic


Label Type Compact Identifier
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MAPK signalingpathway Pathway wikipathways:WP510
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Ycg1 GeneProduct sgd:S000002733
DNA biosynthesis Pathway None
Apc8 GeneProduct None
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Pcl1 GeneProduct sgd:S000005233
Rad26 GeneProduct sgd:S000003796
Sic1 GeneProduct sgd:S000004069
Sic1 GeneProduct sgd:S000004069
Second messanger signaling pathway Pathway None
Cdc5 GeneProduct sgd:S000004603
Cdc34 GeneProduct sgd:S000002461
Orc1 GeneProduct sgd:S000004530
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Mob1 GeneProduct sgd:S000001368
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Tup1 GeneProduct sgd:S000000680
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Phosphate Metabolite cas:14265-44-2
Rad25 GeneProduct sgd:S000001405
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Cks1 GeneProduct sgd:S000000339
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Cdc45 GeneProduct sgd:S000004093
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Swe1 GeneProduct sgd:S000003723
Cdh1 GeneProduct sgd:S000002971
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Pho85 GeneProduct sgd:S000005952
Pds1 GeneProduct sgd:S000002520
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Mik1 GeneProduct None
Condensin GeneProduct None
Cak1 GeneProduct sgd:S000001865
Cdc20 GeneProduct sgd:S000003084
Dam1 GeneProduct sgd:S000003345
Rad53 GeneProduct sgd:S000006074
MCM GeneProduct None
Rad1 GeneProduct sgd:S000005943
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Dcd1 GeneProduct sgd:S000006115
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Mad1 GeneProduct sgd:S000003054
Rad9 GeneProduct sgd:S000002625
APC GeneProduct None
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Mad3 GeneProduct sgd:S000003550
Cyclic AMP Metabolite hmdb:HMDB0000058
Cln1 GeneProduct sgd:S000004812
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Hus1 GeneProduct sgd:S000005424
Apc11 GeneProduct sgd:S000002166
Tem1 GeneProduct sgd:S000004529
Lte1 GeneProduct sgd:S000000022
Pho5 GeneProduct sgd:S000000297
APC GeneProduct None


  1. Taylor SS. Chromosome segregation: dual control ensures fidelity. Curr Biol. 1999;9(15):R562-4. PubMed Europe PMC Scholia
  2. Kang J, Yu H. Kinase signaling in the spindle checkpoint. J Biol Chem. 2009 Jun 5;284(23):15359–63. PubMed Europe PMC Scholia