Omega-9 fatty acid synthesis (WP4351)

This pathway is inspired by the Lipidmaps>Omega-9 and other fatty acids [https://lipidmaps.org/pathway/pathways_maps]. Omega-9 FAs (Fatty acids) are fats which can be obtained from diet, but also produced endogenously. These lipids are monounsaturated (indicating one double bonds in the lipid tail).The position of the double bond is counted from the tail end of the lipid chain. This pathway also indicated saturated fats (without a double bond), such as stearic acid, arachidic acid etc.
last edited

Authors

Eoin Fahy , Ryan Miller , Denise Slenter , Eric Weitz , Egon Willighagen , and Conroy lipids

Cited In

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Organism

Mus musculus

Communities

Lipids and LIPID MAPS

Annotations

Pathway Ontology: fatty acid metabolic pathway unsaturated fatty acid biosynthetic pathway fatty acid elongation pathway

Participants

Label Type Compact Identifier
CoA(20:0) Metabolite lipidmaps:LMFA07050329
Lauric acid Metabolite lipidmaps:LMFA01010012
Myristic acid Metabolite lipidmaps:LMFA01010014
CoA(16:0) Metabolite lipidmaps:LMFA07050360
CoA(16:1(9Z)) Metabolite lipidmaps:LMFA07050359
CoA(18:1(9Z)) Metabolite lipidmaps:LMFA07050356
CoA(18:2(6Z,9Z)) Metabolite lipidmaps:LMFA07050060
CoA(20:1(11Z)) Metabolite lipidmaps:LMFA07050093
CoA(20:2(8Z,11Z)) Metabolite lipidmaps:LMFA07050061
18:2(6Z,9Z) Metabolite lipidmaps:LMFA07050060
Stearic acid Metabolite lipidmaps:LMFA01010018
16:1(9Z) Metabolite lipidmaps:LMFA01030056
CoA(18:0) Metabolite lipidmaps:LMFA07050369
Palmitic acid Metabolite lipidmaps:LMFA01010001
CoA(22:0) Metabolite lipidmaps:LMFA07050289
CoA(24:0) Metabolite lipidmaps:LMFA07050372
CoA(26:0) Metabolite lipidmaps:LMFA07050327
Arachidic acid Metabolite lipidmaps:LMFA01010020
Behenic acid Metabolite lipidmaps:LMFA01010022
Lignoceric acid Metabolite lipidmaps:LMFA01010024
Cerotic acid Metabolite lipidmaps:LMFA01010026
CoA(22:1(13Z)) Metabolite lipidmaps:LMFA07050318
CoA(24:1(15Z)) Metabolite lipidmaps:LMFA07050098
20:2(8Z,11Z) Metabolite lipidmaps:LMFA01030377
CoA(20:3(5Z,8Z,11Z)) Metabolite lipidmaps:LMFA07050062
20:3(5Z,8Z,11Z) Metabolite lipidmaps:LMFA01030381
Oleic acid Metabolite lipidmaps:LMFA01030002
24:1(15Z)) Metabolite lipidmaps:LMFA01030377
cis-erucic acid Metabolite cas:112-86-7
Fads1 GeneProduct ncbigene:76267
Acsl1 GeneProduct ncbigene:14081
Fasn GeneProduct ncbigene:14104
Acsl3 GeneProduct ncbigene:74205
Acsl4 GeneProduct ncbigene:50790
Elovl2 GeneProduct ncbigene:54326
Elovl5 GeneProduct ncbigene:68801
Elovl6 GeneProduct ncbigene:170439
Elovl3 GeneProduct ncbigene:12686
Elovl1 GeneProduct ncbigene:54325
Scd2 GeneProduct ncbigene:20250
Fads2 GeneProduct ncbigene:56473
Acot1 GeneProduct ncbigene:26897
Acot2 GeneProduct ncbigene:171210
Acot1 GeneProduct ncbigene:26897

References

  1. Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, et al. A mouse macrophage lipidome. J Biol Chem. 2010 Dec 17;285(51):39976–85. PubMed Europe PMC Scholia