Mitochondrial long chain fatty acid beta-oxidation (WP448)

Mitochondrial fatty acid β-oxidation (FAO) is crucial in the prodcution of energy, especially during fasting and metabolic stress. Fatty acids (FAs) are oxidized through 4 reaction mechanisms, and this pathway describes the mitochondrial beta-oxidation of dietary long chain fatty acids.
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Niradiz Reyes , Maintenance bot , Daniela Digles , Eric Weitz , Franziska Kreidl , and Denise Slenter

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Caenorhabditis elegans


Lipids and LIPID MAPS


Pathway Ontology: fatty acid beta degradation pathway


Label Type Compact Identifier
Trans-Δ²-Enoyl-CoA Metabolite chebi:10723
dif-1 GeneProduct ncbigene:177530
cpt-2 GeneProduct ncbigene:178025
T08G2.3 GeneProduct ncbigene:181757
F54C8.1 GeneProduct ncbigene:186222
T08B2.7 GeneProduct ncbigene:172310
cpt-1 GeneProduct ncbigene:174912
E04F6.5 GeneProduct ncbigene:174180
F37C12.7 GeneProduct ncbigene:176005
Y65B4BL.5 GeneProduct ncbigene:171643
Y57A10C.6 GeneProduct ncbigene:174881
acs-17 GeneProduct ncbigene:180859


  1. Elle IC, Rødkær SV, Fredens J, Færgeman NJ. A method for measuring fatty acid oxidation in C. elegans. Worm. 2012 Jan 1;1(1):26–30. PubMed Europe PMC Scholia