Envelope proteins and their potential roles in EDMD physiopathology (WP4535)

Schematic model of the nuclear envelope proteins and their potential roles in EDMD physiopathology.
last edited

Authors

Laurent, Marvin M2, AlexanderPico, and Fehrhart

Cited In

Organism

Homo sapiens

Communities

Rare Diseases

Annotations

Disease Ontology: Emery-Dreifuss muscular dystrophy

Pathway Ontology: disease pathway

Participants

Label Type Compact Identifier
ADCY1 GeneProduct ncbigene:107
ADCY2 GeneProduct ncbigene:108
ADCY3 GeneProduct ncbigene:109
ADCY4 GeneProduct ncbigene:196883
ADCY5 GeneProduct ncbigene:111
ADCY6 GeneProduct ncbigene:112
ADCY7 GeneProduct ncbigene:113
ADCY8 GeneProduct ncbigene:114
ADCY9 GeneProduct ncbigene:115
SYNE1 GeneProduct ncbigene:23345
TGFB1 GeneProduct ncbigene:7040
TGFB2 GeneProduct ncbigene:7042
TAZ GeneProduct ncbigene:6901
YY1AP1 GeneProduct ncbigene:55249
TMPO GeneProduct ncbigene:7112
SYNE4 GeneProduct ncbigene:163183
PLEC GeneProduct ncbigene:5339
MAP2K2 GeneProduct ncbigene:5605
Smad3 GeneProduct ncbigene:4088
Cofilin-1 GeneProduct ncbigene:1072
SYNE3 GeneProduct ncbigene:161176
HRAS GeneProduct ncbigene:3265
SOS2 GeneProduct ncbigene:6655
Grb2 GeneProduct ncbigene:2885
SUN GeneProduct ncbigene:23353
NRAS GeneProduct ncbigene:4893
MAP2K1 GeneProduct ncbigene:5604
Smad2 GeneProduct ncbigene:4087
MAPK1 GeneProduct ncbigene:5594
EMD GeneProduct ncbigene:2010
CTGF GeneProduct ncbigene:1490
BANF1 GeneProduct ncbigene:8815
MAPK3 GeneProduct ncbigene:5595
SYNE2 GeneProduct ncbigene:23224
Smad4 GeneProduct ncbigene:4089
TMEM43 GeneProduct ncbigene:79188
ADCY10 GeneProduct ncbigene:55811
MAP3K9 GeneProduct ncbigene:4293
LEMD3 GeneProduct ncbigene:23592
SRF GeneProduct ncbigene:6722
KIF5B GeneProduct ncbigene:3799
KRAS GeneProduct ncbigene:3845
SOS1 GeneProduct ncbigene:6654
LBR GeneProduct ncbigene:3930
RhoA GeneProduct ncbigene:387
TGFB3 GeneProduct ncbigene:7043
MAP3K9 GeneProduct ncbigene:4293
ADCY9 GeneProduct ncbigene:115
ADCY1 GeneProduct ncbigene:107
ADCY10 GeneProduct ncbigene:55811
ADCY4 GeneProduct ncbigene:196883
ADCY7 GeneProduct ncbigene:113
ADCY3 GeneProduct ncbigene:109
ADCY2 GeneProduct ncbigene:108
ADCY8 GeneProduct ncbigene:114
ADCY5 GeneProduct ncbigene:111
ADCY6 GeneProduct ncbigene:112
MAP3K9 GeneProduct ncbigene:4293
MAPK1 GeneProduct ncbigene:5594
MAPK3 GeneProduct ncbigene:5595
Smad2 GeneProduct ncbigene:4087
Smad3 GeneProduct ncbigene:4088
Smad4 GeneProduct ncbigene:4089
Smad3 GeneProduct ncbigene:4088
YY1AP1 GeneProduct ncbigene:55249
TAZ GeneProduct ncbigene:6901
BANF1 GeneProduct ncbigene:8815
SUN GeneProduct ncbigene:23353
SUN GeneProduct ncbigene:23353
BANF1 GeneProduct ncbigene:8815
Smad2 GeneProduct ncbigene:4087

References

  1. Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT. The Pathogenesis and Therapies of Striated Muscle Laminopathies. Front Physiol. 2018 Oct 30;9:1533. PubMed Europe PMC Scholia