Omega-3 / omega-6 fatty acid synthesis (WP4723)
New PW, homology converted
Authors
Denise Slenter , Egon Willighagen , Eric Weitz , and Conroy lipidsCited In
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Organism
Homo sapiensCommunities
Lipids and LIPID MAPSAnnotations
Pathway Ontology: fatty acid elongation pathway amino acid metabolic pathway unsaturated fatty acid biosynthetic pathway fatty acid metabolic pathway fatty acid omega degradation pathway
Participants
| Label | Type | Compact Identifier |
|---|---|---|
| Glycerophospholipids | Metabolite | chebi:37739 |
| Arachidonic acid | Metabolite | lipidmaps:LMFA01030001 |
| Linoleic acid | Metabolite | lipidmaps:LMFA01030120 |
| CoA(18:2(9Z,12Z)) | Metabolite | lipidmaps:LMFA07050343 |
| CoA(18:3(6Z,9Z,12Z)) | Metabolite | lipidmaps:LMFA07050322 |
| CoA(20:2(11Z,14Z)) | Metabolite | lipidmaps:LMFA07050036 |
| CoA(20:3(8Z,11Z,14Z)) | Metabolite | lipidmaps:LMFA07050278 |
| Arachidonoyl-CoA | Metabolite | lipidmaps:LMFA07050288 |
| gamma-Linolenic acid | Metabolite | lipidmaps:LMFA01030141 |
| CoA(22:4) | Metabolite | lipidmaps:LMFA07050129 |
| CoA(24:4) | Metabolite | lipidmaps:LMFA07050139 |
| 20:2(11Z,14Z) | Metabolite | lipidmaps:LMFA01031043 |
| Bishomo-gamma-linolenic acid | Metabolite | lipidmaps:LMFA01030158 |
| CoA(22:5(4Z,7Z,10Z,13Z,16Z)) | Metabolite | lipidmaps:LMFA07050043 |
| alpha-Linolenic acid | Metabolite | lipidmaps:LMFA01030152 |
| CoA(18:3(9Z,12Z,15Z)) | Metabolite | lipidmaps:LMFA07050286 |
| CoA(18:4(6Z,9Z,12Z,15Z)) | Metabolite | lipidmaps:LMFA07050123 |
| CoA(20:4(8Z,11Z,14Z,17Z)) | Metabolite | lipidmaps:LMFA07050134 |
| CoA(20:5) | Metabolite | lipidmaps:LMFA07050122 |
| CoA(22:5(7Z,10Z,13Z,16Z,19Z)) | Metabolite | lipidmaps:LMFA07050131 |
| CoA(22:6) | Metabolite | lipidmaps:LMFA07050121 |
| CoA(24:5(9Z,12Z,15Z,18Z,21Z)) | Metabolite | lipidmaps:LMFA07050141 |
| CoA(24:6) | Metabolite | lipidmaps:LMFA07050127 |
| DHA | Metabolite | lipidmaps:LMFA01030185 |
| 24:6(6Z,9Z,12Z,15Z,18Z,21Z) | Metabolite | lipidmaps:LMFA01030822 |
| 24:5(9Z,12Z,15Z,18Z,21Z) | Metabolite | lipidmaps:LMFA01030821 |
| 22:5(7Z,10Z,13Z,16Z,19Z) | Metabolite | lipidmaps:LMFA04000044 |
| 20:5(5Z,8Z,11Z,14Z,17Z) | Metabolite | lipidmaps:LMFA01030759 |
| 20:4(8Z,11Z,14Z,17Z) | Metabolite | lipidmaps:LMFA01030818 |
| Stearidonic acid | Metabolite | lipidmaps:LMFA01030357 |
| 22:5(4Z,7Z,10Z,13Z,16Z) | Metabolite | lipidmaps:LMFA04000064 |
| 22:4(7Z,10Z,13Z,16Z) | Metabolite | lipidmaps:LMFA01030178 |
| 24:4(9Z,12Z,15Z,18Z) | Metabolite | lipidmaps:LMFA01030819 |
| CoA(22:2(13Z,16Z)) | Metabolite | lipidmaps:LMFA07050037 |
| 22:2(13Z,16Z) | Metabolite | lipidmaps:LMFA01030405 |
| CoA(20:3(11Z,14Z,17Z)) | Metabolite | lipidmaps:LMFA07050044 |
| 20:3(11Z,14Z,17Z) | Metabolite | lipidmaps:LMFA01030378 |
| CoA(24:5(6Z,9Z,12Z,15Z,18Z)) | Metabolite | lipidmaps:LMFA07050042 |
| 24:5(6Z,9Z,12Z,15Z,18Z) | Metabolite | lipidmaps:LMFA01030820 |
| FADS2 | GeneProduct | ensembl:ENSG00000134824 |
| ACSL1 | GeneProduct | ensembl:ENSG00000151726 |
| FADS2 | GeneProduct | ensembl:ENSG00000134824 |
| ACSL3 | GeneProduct | ensembl:ENSG00000123983 |
| ACSL4 | GeneProduct | ensembl:ENSG00000068366 |
| ELOVL2 | GeneProduct | ensembl:ENSG00000197977 |
| ELOVL5 | GeneProduct | ensembl:ENSG00000012660 |
| FADS1 | GeneProduct | ensembl:ENSG00000149485 |
| ACOX1 | GeneProduct | ensembl:ENSG00000161533 |
| ACOX3 | GeneProduct | ensembl:ENSG00000087008 |
| FADS1 | GeneProduct | ensembl:ENSG00000149485 |
| ACOT1 | GeneProduct | uniprot:Q86TX2 |
| ACOT2 | GeneProduct | ensembl:ENSG00000119673 |
| FADS2 | GeneProduct | ensembl:ENSG00000134824 |
| ELOVL2 | GeneProduct | ensembl:ENSG00000197977 |
| ELOVL5 | GeneProduct | ensembl:ENSG00000012660 |
| ACSL1 | GeneProduct | ensembl:ENSG00000151726 |
| ACSL3 | GeneProduct | ensembl:ENSG00000123983 |
| ACSL4 | GeneProduct | ensembl:ENSG00000068366 |
| FADS2 | GeneProduct | ensembl:ENSG00000134824 |
| ACOX1 | GeneProduct | ensembl:ENSG00000161533 |
| ACOX3 | GeneProduct | ensembl:ENSG00000087008 |
| ELOVL2 | GeneProduct | ensembl:ENSG00000197977 |
| ELOVL5 | GeneProduct | ensembl:ENSG00000012660 |
| ACOT1 | GeneProduct | uniprot:Q86TX2 |
| ACOT2 | GeneProduct | ensembl:ENSG00000119673 |
| PLA2G5 | Protein | ensembl:ENSG00000127472 |
| PLA2G6 | Protein | ensembl:ENSG00000184381 |
| PLA2G4A | Protein | ensembl:ENSG00000116711 |
| PLA2G4B | Protein | ensembl:ENSG00000243708 |
| PLA2G5 | Protein | ensembl:ENSG00000127472 |
| PLA2G6 | Protein | ensembl:ENSG00000184381 |
| PLA2G4A | Protein | ensembl:ENSG00000116711 |
| PLA2G4B | Protein | ensembl:ENSG00000243708 |
References
- Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, et al. A mouse macrophage lipidome. J Biol Chem. 2010 Dec 17;285(51):39976–85. PubMed Europe PMC Scholia