Omega-3 / omega-6 fatty acid synthesis (WP4723)

New PW, homology converted
last edited

Authors

Denise Slenter , Egon Willighagen , Eric Weitz , and Conroy lipids

Cited In

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Organism

Homo sapiens

Communities

Lipids and LIPID MAPS

Annotations

Pathway Ontology: fatty acid elongation pathway amino acid metabolic pathway unsaturated fatty acid biosynthetic pathway fatty acid metabolic pathway fatty acid omega degradation pathway

Participants

Label Type Compact Identifier
Glycerophospholipids Metabolite chebi:37739
Arachidonic acid Metabolite lipidmaps:LMFA01030001
Linoleic acid Metabolite lipidmaps:LMFA01030120
CoA(18:2(9Z,12Z)) Metabolite lipidmaps:LMFA07050343
CoA(18:3(6Z,9Z,12Z)) Metabolite lipidmaps:LMFA07050322
CoA(20:2(11Z,14Z)) Metabolite lipidmaps:LMFA07050036
CoA(20:3(8Z,11Z,14Z)) Metabolite lipidmaps:LMFA07050278
Arachidonoyl-CoA Metabolite lipidmaps:LMFA07050288
gamma-Linolenic acid Metabolite lipidmaps:LMFA01030141
CoA(22:4) Metabolite lipidmaps:LMFA07050129
CoA(24:4) Metabolite lipidmaps:LMFA07050139
20:2(11Z,14Z) Metabolite lipidmaps:LMFA01031043
Bishomo-gamma-linolenic acid Metabolite lipidmaps:LMFA01030158
CoA(22:5(4Z,7Z,10Z,13Z,16Z)) Metabolite lipidmaps:LMFA07050043
alpha-Linolenic acid Metabolite lipidmaps:LMFA01030152
CoA(18:3(9Z,12Z,15Z)) Metabolite lipidmaps:LMFA07050286
CoA(18:4(6Z,9Z,12Z,15Z)) Metabolite lipidmaps:LMFA07050123
CoA(20:4(8Z,11Z,14Z,17Z)) Metabolite lipidmaps:LMFA07050134
CoA(20:5) Metabolite lipidmaps:LMFA07050122
CoA(22:5(7Z,10Z,13Z,16Z,19Z)) Metabolite lipidmaps:LMFA07050131
CoA(22:6) Metabolite lipidmaps:LMFA07050121
CoA(24:5(9Z,12Z,15Z,18Z,21Z)) Metabolite lipidmaps:LMFA07050141
CoA(24:6) Metabolite lipidmaps:LMFA07050127
DHA Metabolite lipidmaps:LMFA01030185
24:6(6Z,9Z,12Z,15Z,18Z,21Z) Metabolite lipidmaps:LMFA01030822
24:5(9Z,12Z,15Z,18Z,21Z) Metabolite lipidmaps:LMFA01030821
22:5(7Z,10Z,13Z,16Z,19Z) Metabolite lipidmaps:LMFA04000044
20:5(5Z,8Z,11Z,14Z,17Z) Metabolite lipidmaps:LMFA01030759
20:4(8Z,11Z,14Z,17Z) Metabolite lipidmaps:LMFA01030818
Stearidonic acid Metabolite lipidmaps:LMFA01030357
22:5(4Z,7Z,10Z,13Z,16Z) Metabolite lipidmaps:LMFA04000064
22:4(7Z,10Z,13Z,16Z) Metabolite lipidmaps:LMFA01030178
24:4(9Z,12Z,15Z,18Z) Metabolite lipidmaps:LMFA01030819
CoA(22:2(13Z,16Z)) Metabolite lipidmaps:LMFA07050037
22:2(13Z,16Z) Metabolite lipidmaps:LMFA01030405
CoA(20:3(11Z,14Z,17Z)) Metabolite lipidmaps:LMFA07050044
20:3(11Z,14Z,17Z) Metabolite lipidmaps:LMFA01030378
CoA(24:5(6Z,9Z,12Z,15Z,18Z)) Metabolite lipidmaps:LMFA07050042
24:5(6Z,9Z,12Z,15Z,18Z) Metabolite lipidmaps:LMFA01030820
FADS2 GeneProduct ensembl:ENSG00000134824
ACSL1 GeneProduct ensembl:ENSG00000151726
FADS2 GeneProduct ensembl:ENSG00000134824
ACSL3 GeneProduct ensembl:ENSG00000123983
ACSL4 GeneProduct ensembl:ENSG00000068366
ELOVL2 GeneProduct ensembl:ENSG00000197977
ELOVL5 GeneProduct ensembl:ENSG00000012660
FADS1 GeneProduct ensembl:ENSG00000149485
ACOX1 GeneProduct ensembl:ENSG00000161533
ACOX3 GeneProduct ensembl:ENSG00000087008
FADS1 GeneProduct ensembl:ENSG00000149485
ACOT1 GeneProduct uniprot:Q86TX2
ACOT2 GeneProduct ensembl:ENSG00000119673
FADS2 GeneProduct ensembl:ENSG00000134824
ELOVL2 GeneProduct ensembl:ENSG00000197977
ELOVL5 GeneProduct ensembl:ENSG00000012660
ACSL1 GeneProduct ensembl:ENSG00000151726
ACSL3 GeneProduct ensembl:ENSG00000123983
ACSL4 GeneProduct ensembl:ENSG00000068366
FADS2 GeneProduct ensembl:ENSG00000134824
ACOX1 GeneProduct ensembl:ENSG00000161533
ACOX3 GeneProduct ensembl:ENSG00000087008
ELOVL2 GeneProduct ensembl:ENSG00000197977
ELOVL5 GeneProduct ensembl:ENSG00000012660
ACOT1 GeneProduct uniprot:Q86TX2
ACOT2 GeneProduct ensembl:ENSG00000119673
PLA2G5 Protein ensembl:ENSG00000127472
PLA2G6 Protein ensembl:ENSG00000184381
PLA2G4A Protein ensembl:ENSG00000116711
PLA2G4B Protein ensembl:ENSG00000243708
PLA2G5 Protein ensembl:ENSG00000127472
PLA2G6 Protein ensembl:ENSG00000184381
PLA2G4A Protein ensembl:ENSG00000116711
PLA2G4B Protein ensembl:ENSG00000243708

References

  1. Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, et al. A mouse macrophage lipidome. J Biol Chem. 2010 Dec 17;285(51):39976–85. PubMed Europe PMC Scholia