Omega-9 fatty acid synthesis (WP4724)

New PW, homology converted
last edited

Authors

Denise Slenter and Eric Weitz

Cited In

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Organism

Homo sapiens

Communities

Lipids and LIPID MAPS

Annotations

Pathway Ontology: fatty acid elongation pathway fatty acid metabolic pathway unsaturated fatty acid biosynthetic pathway

Participants

Label Type Compact Identifier
CoA(20:0) Metabolite lipidmaps:LMFA07050329
Lauric acid Metabolite lipidmaps:LMFA01010012
Myristic acid Metabolite lipidmaps:LMFA01010014
CoA(16:0) Metabolite lipidmaps:LMFA07050360
CoA(16:1(9Z)) Metabolite lipidmaps:LMFA07050359
CoA(18:1(9Z)) Metabolite lipidmaps:LMFA07050356
CoA(18:2(6Z,9Z)) Metabolite lipidmaps:LMFA07050060
CoA(20:1(11Z)) Metabolite lipidmaps:LMFA07050093
CoA(20:2(8Z,11Z)) Metabolite lipidmaps:LMFA07050061
18:2(6Z,9Z) Metabolite lipidmaps:LMFA07050060
Stearic acid Metabolite lipidmaps:LMFA01010018
16:1(9Z) Metabolite lipidmaps:LMFA01030056
CoA(18:0) Metabolite lipidmaps:LMFA07050369
Palmitic acid Metabolite lipidmaps:LMFA01010001
CoA(22:0) Metabolite lipidmaps:LMFA07050289
CoA(24:0) Metabolite lipidmaps:LMFA07050372
CoA(26:0) Metabolite lipidmaps:LMFA07050327
Arachidic acid Metabolite lipidmaps:LMFA01010020
Behenic acid Metabolite lipidmaps:LMFA01010022
Lignoceric acid Metabolite lipidmaps:LMFA01010024
Cerotic acid Metabolite lipidmaps:LMFA01010026
CoA(22:1(13Z)) Metabolite lipidmaps:LMFA07050318
CoA(24:1(15Z)) Metabolite lipidmaps:LMFA07050098
20:2(8Z,11Z) Metabolite lipidmaps:LMFA01030377
CoA(20:3(5Z,8Z,11Z)) Metabolite lipidmaps:LMFA07050062
20:3(5Z,8Z,11Z) Metabolite lipidmaps:LMFA01030381
Oleic acid Metabolite lipidmaps:LMFA01030002
24:1(15Z)) Metabolite lipidmaps:LMFA01030377
cis-erucic acid Metabolite cas:112-86-7
FADS1 GeneProduct ensembl:ENSG00000149485
ACSL1 GeneProduct ensembl:ENSG00000151726
FASN GeneProduct ensembl:ENSG00000169710
ACSL3 GeneProduct ensembl:ENSG00000123983
ACSL4 GeneProduct ensembl:ENSG00000068366
ELOVL2 GeneProduct ensembl:ENSG00000197977
ELOVL5 GeneProduct ensembl:ENSG00000012660
ELOVL6 GeneProduct ensembl:ENSG00000170522
ELOVL3 GeneProduct ensembl:ENSG00000119915
ELOVL1 GeneProduct ensembl:ENSG00000066322
FADS2 GeneProduct ensembl:ENSG00000134824
ACOT2 GeneProduct ensembl:ENSG00000119673
SCD5 Protein uniprot:Q86SK9
hSCD1 Protein uniprot:O00767

References

  1. Zhang S, Yang Y, Shi Y. Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells. Biochem J. 2005 May 15;388(Pt 1):135–42. PubMed Europe PMC Scholia
  2. Wang J, Yu L, Schmidt RE, Su C, Huang X, Gould K, et al. Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates. Biochem Biophys Res Commun. 2005 Jul 8;332(3):735–42. PubMed Europe PMC Scholia
  3. Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, et al. A mouse macrophage lipidome. J Biol Chem. 2010 Dec 17;285(51):39976–85. PubMed Europe PMC Scholia