Sphingolipid metabolism: integrated pathway (WP4726)

New PW, homology converted
last edited


Denise Slenter , Kristina Hanspers , Eric Weitz , Conroy lipids , and Egon Willighagen

Cited In


Homo sapiens


Lipids and LIPID MAPS


Pathway Ontology: cholesterol biosynthetic pathway sphingolipid biosynthetic pathway sphingomyelin metabolic pathway sphingolipid metabolic pathway


Label Type Compact Identifier
ATP Metabolite chebi:30616
3-keto-sphinganine Metabolite lipidmaps:LMSP01020002
Palmitoyl-CoA Metabolite lipidmaps:LMFA07050360
Serine Metabolite pubchem.compound:5951
Hexadecanal Metabolite lipidmaps:LMFA06000088
Ethanolamine-phosphate Metabolite pubchem.compound:1015
H2O Metabolite chebi:15377
Sphingosine Metabolite lipidmaps:LMSP01010001
Sphinganine Metabolite lipidmaps:LMSP01020001
Sphinganine-1-phosphate Metabolite lipidmaps:LMSP01050002
C16 SM Metabolite lipidmaps:LMSP03010003
C16 GlcCer Metabolite lipidmaps:LMSP0501AA03
C16DH SM Metabolite lipidmaps:LMSP03010004
C16DH GlcCer Metabolite lipidmaps:LMSP0501AA04
Sphingosine-1-phosphate Metabolite lipidmaps:LMSP01050001
1-Hexadecenal Metabolite lipidmaps:LMFA06000088
CoA(16:0) Metabolite lipidmaps:LMFA07050360
CoA(18:0) Metabolite chebi:15541
CoA(20:0) Metabolite chebi:15527
CoA(22:0) Metabolite cas:24330-89-0
CoA(24:0) Metabolite cas:24305-30-4
CoA(24:1) Metabolite cas:88362-35-0
C16DH-Cer Metabolite lipidmaps:LMSP02020001
CoA(26:0) Metabolite cas:99313-57-2
CoA(26:1) Metabolite lipidmaps:LMFA07050099
ADP Metabolite chebi:456216
C16 Cer Metabolite lipidmaps:LMSP02010004
C18 SM Metabolite lipidmaps:LMSP03010001
C18 GlcCer Metabolite lipidmaps:LMSP0501AA05
C18DH SM Metabolite lipidmaps:LMSP03010020
C18DH GlcCer Metabolite lipidmaps:LMSP0501AA19
C18DH-Cer Metabolite lipidmaps:LMSP02020008
C18 Cer Metabolite lipidmaps:LMSP02010006
C20 SM Metabolite lipidmaps:LMSP03010005
C20 GlcCer Metabolite lipidmaps:LMSP0501AA06
C20DH SM Metabolite lipidmaps:LMSP03010021
C20DH GlcCer Metabolite lipidmaps:LMSP0501AA20
C20DH-Cer Metabolite lipidmaps:LMSP02020009
C20 Cer Metabolite lipidmaps:LMSP02010007
C22 SM Metabolite lipidmaps:LMSP03010006
C22 GlcCer Metabolite lipidmaps:LMSP0501AA07
C22DH SM Metabolite lipidmaps:LMSP03010022
C22DH GlcCer Metabolite lipidmaps:LMSP0501AA21
C22DH-Cer Metabolite lipidmaps:LMSP02020010
C22 Cer Metabolite lipidmaps:LMSP02010008
C24 SM Metabolite lipidmaps:LMSP03010008
C24 GlcCer Metabolite lipidmaps:LMSP0501AA09
C24DH SM Metabolite lipidmaps:LMSP03010024
C24DH GlcCer Metabolite lipidmaps:LMSP0501AA23
C24DH-Cer Metabolite lipidmaps:LMSP02020012
C24 Cer Metabolite lipidmaps:LMSP02010012
C24:1 SM Metabolite lipidmaps:LMSP03010007
C24:1 GlcCer Metabolite lipidmaps:LMSP0501AA08
C24:1DH SM Metabolite lipidmaps:LMSP03010023
C24:1DH GlcCer Metabolite lipidmaps:LMSP0501AA22
C24:1DH-Cer Metabolite lipidmaps:LMSP02020011
C24:1 Cer Metabolite lipidmaps:LMSP02010009
C26:1 SM Metabolite lipidmaps:LMSP03010009
C26:1 GlcCer Metabolite lipidmaps:LMSP0501AA10
C26:1DH SM Metabolite lipidmaps:LMSP03010025
C26:1DH GlcCer Metabolite lipidmaps:LMSP0501AA24
C26:1DH-Cer Metabolite lipidmaps:LMSP02020013
C26:1 Cer Metabolite lipidmaps:LMSP02010010
C26 SM Metabolite lipidmaps:LMSP03010010
C26 GlcCer Metabolite lipidmaps:LMSP0501AA11
C26DH SM Metabolite lipidmaps:LMSP03010026
C26DH GlcCer Metabolite lipidmaps:LMSP0501AA25
C26DH-Cer Metabolite lipidmaps:LMSP02020014
C26 Cer Metabolite lipidmaps:LMSP02010011
Ethanolamine-phosphate Metabolite pubchem.compound:1015
Ppap2a GeneProduct uniprot:O14494
CERK Protein ensembl:ENSG00000100422
SGPP1 Protein ensembl:ENSG00000126821
ASAH1 Protein ensembl:ENSG00000104763
SGMS1 Protein ensembl:ENSG00000198964
SPHK2 Protein ensembl:ENSG00000063176
SGPL1 Protein ensembl:ENSG00000166224
UGCG Protein ensembl:ENSG00000148154
SPTLC1 Protein ensembl:ENSG00000090054
SPHK1 Protein ensembl:ENSG00000176170
DEGS1 Protein ensembl:ENSG00000143753
KDSR Protein ensembl:ENSG00000119537
SPTLC2 Protein ensembl:ENSG00000100596
CERS4 Protein ensembl:ENSG00000090661
CERS5 Protein ensembl:ENSG00000139624
CERS6 Protein ensembl:ENSG00000172292
SMPD1 Protein ensembl:ENSG00000166311
DEGS2 Protein ensembl:ENSG00000168350
SGMS2 Protein ensembl:ENSG00000164023
PLPP3 Protein ensembl:ENSG00000162407
Ppap2c Protein uniprot:O43688
UGT8 Protein ensembl:ENSG00000174607
CERS1 Protein ensembl:ENSG00000223802
CERS4 Protein ensembl:ENSG00000090661
CERS2 Protein ensembl:ENSG00000143418
CERS3 Protein ensembl:ENSG00000154227
SGPP2 Protein ensembl:ENSG00000163082
SPHK2 Protein ensembl:ENSG00000063176
SPHK1 Protein ensembl:ENSG00000176170
SGPL1 Protein ensembl:ENSG00000166224
CERS4 Protein ensembl:ENSG00000090661
CERS2 Protein ensembl:ENSG00000143418
CERS4 Protein ensembl:ENSG00000090661
CERS5 Protein ensembl:ENSG00000139624
CERS6 Protein ensembl:ENSG00000172292
CERK Protein ensembl:ENSG00000100422
UGCG Protein ensembl:ENSG00000148154
SMPD1 Protein ensembl:ENSG00000166311
SGMS1 Protein ensembl:ENSG00000198964
SGMS2 Protein ensembl:ENSG00000164023
UGT8 Protein ensembl:ENSG00000174607
CERS3 Protein ensembl:ENSG00000154227


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