Host-pathogen interaction of human coronaviruses - interferon induction (WP4880)

Figure 8 of review.
last edited


Fehrhart, Egonw, AlexanderPico, Evelo, Eweitz, and Finterly

Cited In


Homo sapiens




Disease Ontology: severe acute respiratory syndrome viral infectious disease

Pathway Ontology: type I interferon signaling pathway signaling pathway


Label Type Compact Identifier
ISRE GeneProduct None
viralRNA Rna None
MAVS GeneProduct ensembl:ENSG00000088888
INF-I Protein None
TICAM1 GeneProduct ncbigene:148022
Innate Immunity Pathway wikipathways:WP4912
IFIH1 GeneProduct ensembl:ENSG00000115267
DDX58 GeneProduct ensembl:ENSG00000107201
RIPK1 GeneProduct ensembl:ENSG00000137275
IKBKE GeneProduct ensembl:ENSG00000263528
IRF3 GeneProduct ensembl:ENSG00000126456
TRAF6 GeneProduct ensembl:ENSG00000175104
CHUK GeneProduct ensembl:ENSG00000213341
MYD88 GeneProduct ensembl:ENSG00000172936
IKBKB GeneProduct ensembl:ENSG00000104365
TRAF3 GeneProduct ensembl:ENSG00000131323
NFKB1 GeneProduct ensembl:ENSG00000109320
TBK1 GeneProduct ensembl:ENSG00000183735
JAK1 GeneProduct ensembl:ENSG00000162434
TLR7 GeneProduct ensembl:ENSG00000196664
IKBKG GeneProduct ensembl:ENSG00000269335
NFKBIA GeneProduct ensembl:ENSG00000100906
OAS1 GeneProduct ensembl:ENSG00000089127
PKR GeneProduct ensembl:ENSG00000055332
PLpro (nsp3) Protein refseq:YP_009725299.1
MAP3K7 GeneProduct ensembl:ENSG00000135341
MAPK8 GeneProduct ensembl:ENSG00000107643
MAPK14 GeneProduct ensembl:ENSG00000112062
JUN GeneProduct ensembl:ENSG00000177606
FOS GeneProduct ensembl:ENSG00000170345
IFNAR1 GeneProduct ensembl:ENSG00000142166
IFNAR2 GeneProduct ensembl:ENSG00000159110
TYK2 GeneProduct ensembl:ENSG00000105397
STAT1 GeneProduct ensembl:ENSG00000115415
STAT2 GeneProduct ensembl:ENSG00000170581
IRF9 GeneProduct ensembl:ENSG00000213928
INF-I Protein None
INF-I Protein None
ISRE GeneProduct None
ISGs Protein None
OAS2 GeneProduct ensembl:ENSG00000111335
OAS3 GeneProduct ensembl:ENSG00000111331
6 Protein uniprot:P59634
nsp3 Protein RefSeq
nsp15 Protein RefSeq
4a Protein RefSeq
M Protein uniprot:P59596
N Protein wikidata:Q89457519
PLPro Protein RefSeq
9b Protein uniprot:P59636
4b Protein RefSeq
S Protein RefSeq
E Protein uniprot:P59637
4a Protein RefSeq
PLPro Protein RefSeq
S Protein uniprot:694009
3a Protein uniprot:P59632
7a Protein uniprot:P59635
3b Protein uniprot:P59633
8b Protein Uniprot-TrEMBL
8ab Protein Uniprot-TrEMBL


  1. Fung TS, Liu DX. Human Coronavirus: Host-Pathogen Interaction. Annu Rev Microbiol. 2019 Sep 8;73:529–57. PubMed Europe PMC Scholia