Biosynthesis of aldosterone and cortisol (WP508)

Keywords: 17-oh aldosterone biochemistry biosynthesis corticosterone cortisol metabolism metabolism of pregnenolone progesterone steroid
last edited

Authors

Thomas, MaintBot, Khanspers, Christine Chichester, and Eweitz

Cited In

Organism

Rattus norvegicus

Communities

Annotations

Pathway Ontology: C21-steroid hormone biosynthetic pathway

Participants

Label Type Compact Identifier
Hsd3b1 GeneProduct ensembl:ENSRNOG00000019441
Cortisol Metabolite hmdb:HMDB0000063
18-OH Corticosterone Metabolite pubchem.compound:11222
Pregnenolone Metabolite chebi:16581
Progesterone Metabolite chebi:17026
17-OH Pregnenolone Metabolite pubchem.compound:91451
Hsd3b1 GeneProduct ensembl:ENSRNOG00000019441
Cyp17a1 GeneProduct ensembl:ENSRNOG00000020035
Cyp11b1 GeneProduct ensembl:ENSRNOG00000037385
Cyp11b2 GeneProduct ensembl:ENSRNOG00000030111
Corticosterone Metabolite hmdb:HMDB0001547
Cyp11a1 GeneProduct ensembl:ENSRNOG00000008074
Cyp11b1 GeneProduct ensembl:ENSRNOG00000037385
Cyp17a1 GeneProduct ensembl:ENSRNOG00000020035
Cholesterol Metabolite chebi:16113
Aldosterone Metabolite hmdb:HMDB0000037
Cyp21a1 GeneProduct ensembl:ENSRNOG00000000428
Cyp21a1 GeneProduct ensembl:ENSRNOG00000000428
17-OH Progesterone Metabolite None
11-deoxycortisol Metabolite hmdb:HMDB0000015
Cyp11b2 GeneProduct ensembl:ENSRNOG00000030111
Deoxy-corticosterone Metabolite chebi:16973

References