Malignant pleural mesothelioma (WP5087)

Mesothelioma
last edited

Authors

Ziska, Marvin M2, Eweitz, Finterly, Egonw, and L Dupuis

Cited In

Organism

Homo sapiens

Communities

Annotations

Pathway Ontology: disease pathway altered autophagy pathway

Disease Ontology: malignant pleural mesothelioma

Cell Type Ontology: mesothelial cell mesothelial cell of pleura

Participants

Label Type Compact Identifier
TCF7L1 GeneProduct ensembl:ENSG00000152284
TCF7 GeneProduct ensembl:ENSG00000081059
14-3-3 Protein uniprot:A0A0J9YWE8
ASXL1 GeneProduct ensembl:ENSG00000171456
CTGF GeneProduct ensembl:ENSG00000118523
TGFB1 GeneProduct ensembl:ENSG00000105329
RBBP4 GeneProduct ensembl:ENSG00000162521
MAPK8 GeneProduct ensembl:ENSG00000107643
MYC GeneProduct ensembl:ENSG00000136997
PLCB4 GeneProduct ensembl:ENSG00000101333
KDM6A GeneProduct ensembl:ENSG00000147050
PORCN GeneProduct ensembl:ENSG00000102312
CSF2 GeneProduct ensembl:ENSG00000164400
SUZ12 GeneProduct ensembl:ENSG00000178691
PD-L1 GeneProduct ensembl:ENSG00000120217
RASSF1 GeneProduct ensembl:ENSG00000068028
DKK2 GeneProduct ensembl:ENSG00000155011
Ca2+ Metabolite chebi:29108
RING1 GeneProduct ensembl:ENSG00000204227
AREG GeneProduct ensembl:ENSG00000109321
ITGB1 GeneProduct ensembl:ENSG00000150093
BARD1 GeneProduct ensembl:ENSG00000138376
ITGA1 GeneProduct ensembl:ENSG00000213949
CXCL12 GeneProduct ensembl:ENSG00000107562
PHC1 GeneProduct ensembl:ENSG00000111752
TGFA GeneProduct ensembl:ENSG00000163235
SOST GeneProduct ensembl:ENSG00000167941
PDGFRA GeneProduct ensembl:ENSG00000134853
RASSF4 GeneProduct ensembl:ENSG00000107551
BTC GeneProduct ensembl:ENSG00000174808
HCFC1 GeneProduct ensembl:ENSG00000172534
KMT2C GeneProduct ensembl:ENSG00000055609
ACTA2 GeneProduct ensembl:ENSG00000107796
FGF2 GeneProduct ensembl:ENSG00000138685
BAG2 GeneProduct ensembl:ENSG00000112208
DDIT3 GeneProduct ensembl:ENSG00000175197
Unfolded protein response Pathway wikipathways:WP4925
RASSF3 GeneProduct ensembl:ENSG00000153179
ITPR3 GeneProduct ensembl:ENSG00000096433
EED GeneProduct ensembl:ENSG00000074266
IGF1 GeneProduct ensembl:ENSG00000017427
IDO1 GeneProduct ensembl:ENSG00000131203
VGLL4 GeneProduct ensembl:ENSG00000144560
CYCS GeneProduct ensembl:ENSG00000172115
CCND1 GeneProduct ensembl:ENSG00000110092
FGF1 GeneProduct ensembl:ENSG00000113578
MCU GeneProduct ensembl:ENSG00000156026
HGF GeneProduct ensembl:ENSG00000019991
let-7 Rna ensembl:ENSG00000284520
LAMA1 GeneProduct ensembl:ENSG00000101680
MYC GeneProduct ensembl:ENSG00000136997
WIF1 GeneProduct ensembl:ENSG00000156076
LGALS9 GeneProduct ensembl:ENSG00000168961
VEGFA GeneProduct ensembl:ENSG00000112715
RASSF2 GeneProduct ensembl:ENSG00000101265
EZH2 GeneProduct ensembl:ENSG00000106462
CER1 GeneProduct ensembl:ENSG00000147869
RASSF7 GeneProduct ensembl:ENSG00000099849
RAF GeneProduct ensembl:ENSG00000132155
ACTA1 GeneProduct ensembl:ENSG00000143632
FN1 GeneProduct ensembl:ENSG00000115414
IGF1R GeneProduct ensembl:ENSG00000140443
ATF3 GeneProduct ensembl:ENSG00000162772
SLC3A2 GeneProduct ensembl:ENSG00000168003
COL4A1 GeneProduct ensembl:ENSG00000187498
PPARGC1A GeneProduct ensembl:ENSG00000109819
NOTUM GeneProduct ensembl:ENSG00000185269
glucose Metabolite chebi:17234
DKK4 GeneProduct ensembl:ENSG00000104371
BMI1 GeneProduct ensembl:ENSG00000168283
IL6 GeneProduct ensembl:ENSG00000136244
FOXM1 GeneProduct ensembl:ENSG00000111206
DKK1 GeneProduct ensembl:ENSG00000107984
LAMC1 GeneProduct ensembl:ENSG00000135862
MDM4 GeneProduct ensembl:ENSG00000198625
SERPINF1 GeneProduct ensembl:ENSG00000132386
CTGF GeneProduct ensembl:ENSG00000118523
SPARC GeneProduct ensembl:ENSG00000113140
ACTB GeneProduct ensembl:ENSG00000075624
CSF1 GeneProduct ensembl:ENSG00000184371
LIMD1 GeneProduct ensembl:ENSG00000144791
RASSF6 GeneProduct ensembl:ENSG00000169435
FGFR1 GeneProduct ensembl:ENSG00000077782
SLC2A1 GeneProduct ensembl:ENSG00000117394
CCL2 GeneProduct ensembl:ENSG00000108691
IL10 GeneProduct ensembl:ENSG00000136634
CTNNA1 GeneProduct ensembl:ENSG00000044115
CD44 GeneProduct ensembl:ENSG00000026508
FGF2 GeneProduct ensembl:ENSG00000138685
HGF GeneProduct ensembl:ENSG00000019991
MET GeneProduct ensembl:ENSG00000105976
RASSF5 GeneProduct ensembl:ENSG00000266094
LIN28B GeneProduct ensembl:ENSG00000187772
YY1 GeneProduct ensembl:ENSG00000100811
KITLG GeneProduct ensembl:ENSG00000049130
RNF2 GeneProduct ensembl:ENSG00000121481
HBEGF GeneProduct ensembl:ENSG00000113070
KIT GeneProduct ensembl:ENSG00000157404
EGFR GeneProduct ensembl:ENSG00000146648
TCA cycle Pathway wikipathways:WP78
CCL2 GeneProduct ensembl:ENSG00000108691
BRCA1 GeneProduct ensembl:ENSG00000012048
CDK4 GeneProduct ensembl:ENSG00000135446
Histone modifications Pathway wikipathways:WP2369
TP53 GeneProduct ensembl:ENSG00000141510
BCL2 GeneProduct ensembl:ENSG00000171791
CDKN2A GeneProduct ensembl:ENSG00000147889
BAX GeneProduct ensembl:ENSG00000087088
RAGE GeneProduct ensembl:ENSG00000204305
CNNE1 GeneProduct ensembl:ENSG00000105173
14-3-3 Protein uniprot:A0A0J9YWE8
HIF1A GeneProduct ensembl:ENSG00000100644
PIP3 Metabolite chebi:16618
MCL1 GeneProduct ensembl:ENSG00000143384
MMP9 GeneProduct ensembl:ENSG00000100985
CDK7 GeneProduct ensembl:ENSG00000134058
PDK1 GeneProduct ensembl:ENSG00000152256
MAP3K5 GeneProduct ensembl:ENSG00000197442
NF2 GeneProduct ensembl:ENSG00000186575
RAS GeneProduct ensembl:ENSG00000174775
NF-KB GeneProduct ensembl:ENSG00000109320
DNA repair Pathway wikipathways:WP4946
MEK5 GeneProduct ensembl:ENSG00000137764
GRB2 GeneProduct ensembl:ENSG00000177885
TSC1 GeneProduct ensembl:ENSG00000165699
CUL1 GeneProduct ensembl:ENSG00000055130
ATM GeneProduct ensembl:ENSG00000149311
STAT GeneProduct ensembl:ENSG00000115415
SP1 GeneProduct ensembl:ENSG00000185591
ROS Metabolite chebi:70982
MAPK14 GeneProduct ensembl:ENSG00000112062
SHC GeneProduct ensembl:ENSG00000160691
SAV1 GeneProduct ensembl:ENSG00000151748
ERK2 GeneProduct ensembl:ENSG00000100030
LATS1 GeneProduct ensembl:ENSG00000131023
ATG13 GeneProduct ensembl:ENSG00000175224
JAK GeneProduct ensembl:ENSG00000162434
CDKN1A GeneProduct ensembl:ENSG00000124762
CDK2 GeneProduct ensembl:ENSG00000123374
Cell cycle Pathway wikipathways:WP179
SETD2 GeneProduct ensembl:ENSG00000181555
Angiogenesis Pathway wikipathways:WP1993
ULK2 GeneProduct ensembl:ENSG00000083290
HMGB1 GeneProduct ensembl:ENSG00000189403
c-fos Metabolite chebi:62519
MMP2 GeneProduct ensembl:ENSG00000087245
MAP2K4 GeneProduct ensembl:ENSG00000065559
E2F1 GeneProduct ensembl:ENSG00000101412
LATS2 GeneProduct ensembl:ENSG00000150457
PDGF GeneProduct ensembl:ENSG00000197461
GDP Metabolite chebi:17552
BTRC GeneProduct ensembl:ENSG00000166167
MAX GeneProduct ensembl:ENSG00000125952
KIBRA GeneProduct ensembl:ENSG00000113645
Cyclin D GeneProduct ensembl:ENSG00000110092
GABPA GeneProduct ensembl:ENSG00000154727
IL-1B GeneProduct ensembl:ENSG00000125538
FOXO1 GeneProduct ensembl:ENSG00000150907
PUMA GeneProduct ensembl:ENSG00000105327
MST1 GeneProduct ensembl:ENSG00000173531
ERK1 GeneProduct ensembl:ENSG00000102882
EIF4 GeneProduct ensembl:ENSG00000114867
c-jun GeneProduct ensembl:ENSG00000177606
NLRP3 GeneProduct ensembl:ENSG00000162711
p16INK4A GeneProduct uniprot:P42771
VEGF GeneProduct ensembl:ENSG00000112715
FAK GeneProduct ensembl:ENSG00000169398
RHEB GeneProduct ensembl:ENSG00000106615
MDM2 GeneProduct ensembl:ENSG00000135679
AJUBA GeneProduct ensembl:ENSG00000129474
SETD5 GeneProduct ensembl:ENSG00000168137
RPS6KA1 GeneProduct ensembl:ENSG00000117676
MAP2K1 GeneProduct ensembl:ENSG00000169032
MAP3K9 GeneProduct ensembl:ENSG00000006432
PIGF GeneProduct ensembl:ENSG00000151665
fra-1 GeneProduct ensembl:ENSG00000175592
TEAD1 GeneProduct ensembl:ENSG00000187079
TSC2 GeneProduct ensembl:ENSG00000103197
PIP2 Metabolite chebi:18348
CASPASE-1 GeneProduct ensembl:ENSG00000137752
AMOT GeneProduct ensembl:ENSG00000126016
RNS Metabolite wikidata:Q225595
DR5 GeneProduct ensembl:ENSG00000196363
4E-BP GeneProduct ensembl:ENSG00000187840
SRC GeneProduct ensembl:ENSG00000197122
BAP1 GeneProduct ensembl:ENSG00000163930
PTEN GeneProduct ensembl:ENSG00000171862
ERK5 GeneProduct ensembl:ENSG00000166484
MAP2K6 GeneProduct ensembl:ENSG00000108984
TERT GeneProduct ensembl:ENSG00000164362
BECLIN1 GeneProduct ensembl:ENSG00000126581
GTP Metabolite chebi:37565
BAK GeneProduct ensembl:ENSG00000030110
Apoptosis Pathway wikipathways:WP1772
ULK1 GeneProduct ensembl:ENSG00000177169
SETDB1 GeneProduct ensembl:ENSG00000143379
MAD1 GeneProduct ensembl:ENSG00000002822
BCLXL GeneProduct ensembl:ENSG00000171791
PRB1 GeneProduct ensembl:ENSG00000251655
p14ARF Protein uniprot:Q8N726
SOS GeneProduct ensembl:ENSG00000115904
STAT GeneProduct ensembl:ENSG00000115415
AP2 GeneProduct ensembl:ENSG00000170323
CCND1 GeneProduct ensembl:ENSG00000110092
FIP200 GeneProduct ensembl:ENSG00000023287
RAS GeneProduct ensembl:ENSG00000174775
MKNK1 GeneProduct ensembl:ENSG00000079277
MAPKAPK2 GeneProduct ensembl:ENSG00000162889
YAP GeneProduct ensembl:ENSG00000137693
WWTR1 GeneProduct ensembl:ENSG00000018408
MDM2 GeneProduct ensembl:ENSG00000135679
P21 GeneProduct ensembl:ENSG00000124762
BAX GeneProduct ensembl:ENSG00000087088
E2F1 GeneProduct ensembl:ENSG00000101412
PRB1 GeneProduct ensembl:ENSG00000251655
HMGB1 GeneProduct ensembl:ENSG00000189403
HMGB1 GeneProduct ensembl:ENSG00000189403
PRAS40 GeneProduct ensembl:ENSG00000204673
TEL2 GeneProduct ensembl:ENSG00000100726
TTI1 GeneProduct ensembl:ENSG00000101407
MLST8 GeneProduct ensembl:ENSG00000167965
DEPTOR GeneProduct ensembl:ENSG00000155792
MTOR GeneProduct ensembl:ENSG00000198793
HMGB1 GeneProduct ensembl:ENSG00000189403
IL-1B GeneProduct ensembl:ENSG00000125538
Pro IL-1B GeneProduct ensembl:ENSG00000125538
P21 GeneProduct ensembl:ENSG00000124762
YAP GeneProduct ensembl:ENSG00000137693
WWTR1 GeneProduct ensembl:ENSG00000018408
Wnt signaling Pathway wikipathways:WP428
Autophagy Pathway wikipathways:WP4923
Cell migration Pathway wikipathways:WP4561
NF-KB GeneProduct ensembl:ENSG00000109320
SRC GeneProduct ensembl:ENSG00000197122
NF2 GeneProduct ensembl:ENSG00000186575
PAK1 GeneProduct ensembl:ENSG00000149269
PAK2 GeneProduct ensembl:ENSG00000180370
PAK3 GeneProduct ensembl:ENSG00000077264
PAK4 GeneProduct ensembl:ENSG00000130669
PAK5 GeneProduct ensembl:ENSG00000101349
PAK6 GeneProduct ensembl:ENSG00000137843
MAPK signaling pathway Pathway wikipathways:WP382
Angiogenesis Pathway wikipathways:WP1993
VEGFB GeneProduct ensembl:ENSG00000173511
VEGFC GeneProduct ensembl:ENSG00000150630
VEGFD GeneProduct ensembl:ENSG00000165197
TGFB1 GeneProduct ensembl:ENSG00000105329
IL6 GeneProduct ensembl:ENSG00000136244
PDGFA GeneProduct ensembl:ENSG00000197461
PDGFB GeneProduct ensembl:ENSG00000100311
PDGFC GeneProduct ensembl:ENSG00000145431
PDGFD GeneProduct ensembl:ENSG00000170962
MMP2 GeneProduct ensembl:ENSG00000087245
MMP3 GeneProduct ensembl:ENSG00000149968
MMP9 GeneProduct ensembl:ENSG00000100985
MMP14 GeneProduct ensembl:ENSG00000157227
EGF GeneProduct ensembl:ENSG00000138798
FGFR2 GeneProduct ensembl:ENSG00000066468
FGFR3 GeneProduct ensembl:ENSG00000068078
FGFR4 GeneProduct ensembl:ENSG00000160867
IGF2 GeneProduct ensembl:ENSG00000167244
MET GeneProduct ensembl:ENSG00000105976
PDGFRB GeneProduct ensembl:ENSG00000113721
COL4A2 GeneProduct ensembl:ENSG00000134871
COL4A3 GeneProduct ensembl:ENSG00000169031
COL4A4 GeneProduct ensembl:ENSG00000081052
COL4A5 GeneProduct ensembl:ENSG00000188153
COL4A6 GeneProduct ensembl:ENSG00000197565
LAMA2 GeneProduct ensembl:ENSG00000196569
LAMA3 GeneProduct ensembl:ENSG00000053747
LAMA4 GeneProduct ensembl:ENSG00000112769
LAMA5 GeneProduct ensembl:ENSG00000130702
LAMB1 GeneProduct ensembl:ENSG00000091136
LAMB2 GeneProduct ensembl:ENSG00000172037
LAMB3 GeneProduct ensembl:ENSG00000196878
LAMC2 GeneProduct ensembl:ENSG00000058085
LAMC3 GeneProduct ensembl:ENSG00000050555
ITGA2 GeneProduct ensembl:ENSG00000164171
ITGA3 GeneProduct ensembl:ENSG00000005884
ITGA4 GeneProduct ensembl:ENSG00000115232
ITGAV GeneProduct ensembl:ENSG00000138448
ITGA6 GeneProduct ensembl:ENSG00000091409
ITGB2 GeneProduct ensembl:ENSG00000160255
ITGB3 GeneProduct ensembl:ENSG00000259207
ITGB4 GeneProduct ensembl:ENSG00000132470
FN1 GeneProduct ensembl:ENSG00000115414
COL4A1 GeneProduct ensembl:ENSG00000187498
COL4A2 GeneProduct ensembl:ENSG00000134871
COL4A3 GeneProduct ensembl:ENSG00000169031
COL4A4 GeneProduct ensembl:ENSG00000081052
COL4A5 GeneProduct ensembl:ENSG00000188153
COL4A6 GeneProduct ensembl:ENSG00000197565
LAMA1 GeneProduct ensembl:ENSG00000101680
LAMC1 GeneProduct ensembl:ENSG00000135862
LAMA2 GeneProduct ensembl:ENSG00000196569
LAMA3 GeneProduct ensembl:ENSG00000053747
LAMA4 GeneProduct ensembl:ENSG00000112769
LAMA5 GeneProduct ensembl:ENSG00000130702
LAMB1 GeneProduct ensembl:ENSG00000091136
LAMB2 GeneProduct ensembl:ENSG00000172037
LAMB3 GeneProduct ensembl:ENSG00000196878
LAMC2 GeneProduct ensembl:ENSG00000058085
LAMC3 GeneProduct ensembl:ENSG00000050555
CCL4 GeneProduct ensembl:ENSG00000275302
CXCL10 GeneProduct ensembl:ENSG00000169245
CXCL5 GeneProduct ensembl:ENSG00000163735
CXCL12 GeneProduct ensembl:ENSG00000107562
TGFB1 GeneProduct ensembl:ENSG00000105329
VEGFA GeneProduct ensembl:ENSG00000112715
VEGFB GeneProduct ensembl:ENSG00000173511
VEGFC GeneProduct ensembl:ENSG00000150630
VEGFD GeneProduct ensembl:ENSG00000165197
glucose Metabolite chebi:17234
SLC7A5 GeneProduct ensembl:ENSG00000103257
Arginine Metabolite chebi:29016
Arginine Metabolite chebi:29016
Tryptophan Metabolite chebi:16828
Tryptophan Metabolite chebi:16828
Kynurenine Metabolite chebi:28683
IL34 GeneProduct ensembl:ENSG00000157368
CXCL5 GeneProduct ensembl:ENSG00000163735
CXCL12 GeneProduct ensembl:ENSG00000107562
TGFB1 GeneProduct ensembl:ENSG00000105329
CXCL5 GeneProduct ensembl:ENSG00000163735
CXCL1 GeneProduct ensembl:ENSG00000163739
IL6 GeneProduct ensembl:ENSG00000136244
CXCL12 GeneProduct ensembl:ENSG00000107562
CSF3 GeneProduct ensembl:ENSG00000108342
PD-L1 GeneProduct ensembl:ENSG00000120217
IL10 GeneProduct ensembl:ENSG00000136634
prostaglandin E2 Metabolite chebi:15551
CDH5 GeneProduct ensembl:ENSG00000179776
CDH1 GeneProduct ensembl:ENSG00000039068
CDH10 GeneProduct ensembl:ENSG00000040731
CDH17 GeneProduct ensembl:ENSG00000079112
CDH9 GeneProduct ensembl:ENSG00000113100
CDH16 GeneProduct ensembl:ENSG00000166589
CDH6 GeneProduct ensembl:ENSG00000113361
CDH13 GeneProduct ensembl:ENSG00000140945
CDH20 GeneProduct ensembl:ENSG00000101542
CDH2 GeneProduct ensembl:ENSG00000170558
CDH19 GeneProduct ensembl:ENSG00000071991
CDH22 GeneProduct ensembl:ENSG00000149654
CDH8 GeneProduct ensembl:ENSG00000150394
CDH24 GeneProduct ensembl:ENSG00000139880
CDH18 GeneProduct ensembl:ENSG00000145526
CDH12 GeneProduct ensembl:ENSG00000154162
CDH7 GeneProduct ensembl:ENSG00000081138
CDH15 GeneProduct ensembl:ENSG00000129910
CDH11 GeneProduct ensembl:ENSG00000140937
CDH3 GeneProduct ensembl:ENSG00000062038
CDH4 GeneProduct ensembl:ENSG00000179242
PRKAB2 GeneProduct ensembl:ENSG00000131791
PRKAB1 GeneProduct ensembl:ENSG00000111725
PRKAA2 GeneProduct ensembl:ENSG00000162409
PRKAG1 GeneProduct ensembl:ENSG00000181929
PRKAA1 GeneProduct ensembl:ENSG00000132356
PRKAG2 GeneProduct ensembl:ENSG00000106617
PRKAG3 GeneProduct ensembl:ENSG00000115592
FGFR2 GeneProduct ensembl:ENSG00000066468
KDR GeneProduct ensembl:ENSG00000128052
INSR GeneProduct ensembl:ENSG00000171105
FGFR3 GeneProduct ensembl:ENSG00000068078
IGF1R GeneProduct ensembl:ENSG00000140443
KIT GeneProduct ensembl:ENSG00000157404
FGFR1 GeneProduct ensembl:ENSG00000077782
EPHA2 GeneProduct ensembl:ENSG00000142627
EGFR GeneProduct ensembl:ENSG00000146648
CSF1R GeneProduct ensembl:ENSG00000182578
FGFR4 GeneProduct ensembl:ENSG00000160867
FLT1 GeneProduct ensembl:ENSG00000102755
FLT4 GeneProduct ensembl:ENSG00000037280
NGFR GeneProduct ensembl:ENSG00000064300
MET GeneProduct ensembl:ENSG00000105976
PDGFRA GeneProduct ensembl:ENSG00000134853
PDGFRB GeneProduct ensembl:ENSG00000113721
TEK GeneProduct ensembl:ENSG00000120156
FLT3 GeneProduct ensembl:ENSG00000122025
NTRK1 GeneProduct ensembl:ENSG00000198400
NTRK2 GeneProduct ensembl:ENSG00000148053
RAS GeneProduct ensembl:ENSG00000174775
MOB1A GeneProduct ensembl:ENSG00000114978
EFNA1 GeneProduct ensembl:ENSG00000169242
FGF1 GeneProduct ensembl:ENSG00000113578
FGF11 GeneProduct ensembl:ENSG00000161958
FGF10 GeneProduct ensembl:ENSG00000070193
EFNA2 GeneProduct ensembl:ENSG00000099617
EGF GeneProduct ensembl:ENSG00000138798
FGF12 GeneProduct ensembl:ENSG00000114279
CSF1 GeneProduct ensembl:ENSG00000184371
ANGPT4 GeneProduct ensembl:ENSG00000101280
ANGPT2 GeneProduct ensembl:ENSG00000091879
ANGPT1 GeneProduct ensembl:ENSG00000154188
VEGFA GeneProduct ensembl:ENSG00000112715
EFNA3 GeneProduct ensembl:ENSG00000143590
EFNA4 GeneProduct ensembl:ENSG00000243364
EFNA5 GeneProduct ensembl:ENSG00000184349
FGF14 GeneProduct ensembl:ENSG00000102466
FGF5 GeneProduct ensembl:ENSG00000138675
FGF19 GeneProduct ensembl:ENSG00000162344
FGF17 GeneProduct ensembl:ENSG00000158815
FGF18 GeneProduct ensembl:ENSG00000156427
FGF2 GeneProduct ensembl:ENSG00000138685
FGF3 GeneProduct ensembl:ENSG00000186895
FGF4 GeneProduct ensembl:ENSG00000075388
FGF6 GeneProduct ensembl:ENSG00000111241
FGF7 GeneProduct ensembl:ENSG00000140285
FGF8 GeneProduct ensembl:ENSG00000107831
FGF9 GeneProduct ensembl:ENSG00000102678
VEGFD GeneProduct ensembl:ENSG00000165197
HGF GeneProduct ensembl:ENSG00000019991
IGF1 GeneProduct ensembl:ENSG00000017427
IGF2 GeneProduct ensembl:ENSG00000167244
INS GeneProduct ensembl:ENSG00000254647
KITLG GeneProduct ensembl:ENSG00000049130
FLT3LG GeneProduct ensembl:ENSG00000090554
VEGFC GeneProduct ensembl:ENSG00000150630
VEGFB GeneProduct ensembl:ENSG00000173511
PDGFB GeneProduct ensembl:ENSG00000100311
PGF GeneProduct ensembl:ENSG00000119630
PDGFA GeneProduct ensembl:ENSG00000197461
NGF GeneProduct ensembl:ENSG00000134259
PDGFC GeneProduct ensembl:ENSG00000145431
FGF21 GeneProduct ensembl:ENSG00000105550
FGF23 GeneProduct ensembl:ENSG00000118972
FGF22 GeneProduct ensembl:ENSG00000070388
PDGFD GeneProduct ensembl:ENSG00000170962
FGF20 GeneProduct ensembl:ENSG00000078579
FGF13 GeneProduct ensembl:ENSG00000129682
FGF19 GeneProduct ensembl:ENSG00000162344
NTF3 GeneProduct ensembl:ENSG00000185652
NTF4 GeneProduct ensembl:ENSG00000225950
BDNF GeneProduct ensembl:ENSG00000176697
TGFA GeneProduct ensembl:ENSG00000163235
ROS Metabolite chebi:70982
VEGFA GeneProduct ensembl:ENSG00000112715
VEGFB GeneProduct ensembl:ENSG00000173511
VEGFC GeneProduct ensembl:ENSG00000150630
VEGFD GeneProduct ensembl:ENSG00000165197
CCL5 GeneProduct ensembl:ENSG00000271503
CD47 GeneProduct ensembl:ENSG00000196776
ACTC1 GeneProduct ensembl:ENSG00000159251
ACTG1 GeneProduct ensembl:ENSG00000184009
ACTG2 GeneProduct ensembl:ENSG00000163017
ITGB1 GeneProduct ensembl:ENSG00000150093
ITGA1 GeneProduct ensembl:ENSG00000213949
ITGA2 GeneProduct ensembl:ENSG00000164171
ITGA3 GeneProduct ensembl:ENSG00000005884
ITGA4 GeneProduct ensembl:ENSG00000115232
ITGAV GeneProduct ensembl:ENSG00000138448
ITGA6 GeneProduct ensembl:ENSG00000091409
CTNNA2 GeneProduct ensembl:ENSG00000066032
CTNNA3 GeneProduct ensembl:ENSG00000183230
MOB1B GeneProduct ensembl:ENSG00000173542
WWTR1 GeneProduct ensembl:ENSG00000018408
TEAD2 GeneProduct ensembl:ENSG00000074219
TEAD3 GeneProduct ensembl:ENSG00000007866
TEAD4 GeneProduct ensembl:ENSG00000197905
STK3 GeneProduct ensembl:ENSG00000104375
MAPK9 GeneProduct ensembl:ENSG00000050748
MAPK10 GeneProduct ensembl:ENSG00000109339
MAPK8 GeneProduct ensembl:ENSG00000107643
MAPK9 GeneProduct ensembl:ENSG00000050748
MAPK10 GeneProduct ensembl:ENSG00000109339
MINK1 GeneProduct ensembl:ENSG00000141503
TNIK GeneProduct ensembl:ENSG00000154310
MAP4K1 GeneProduct ensembl:ENSG00000104814
MAP4K2 GeneProduct ensembl:ENSG00000168067
MAP4K4 GeneProduct ensembl:ENSG00000071054
MAP4K3 GeneProduct ensembl:ENSG00000011566
STK38L GeneProduct ensembl:ENSG00000211455
NDRG1 GeneProduct ensembl:ENSG00000104419
FZD3 GeneProduct ensembl:ENSG00000104290
FZD8 GeneProduct ensembl:ENSG00000177283
FZD10 GeneProduct ensembl:ENSG00000111432
FZD7 GeneProduct ensembl:ENSG00000155760
FZD4 GeneProduct ensembl:ENSG00000106483
FZD1 GeneProduct ensembl:ENSG00000157240
FZD6 GeneProduct ensembl:ENSG00000164930
FZD5 GeneProduct ensembl:ENSG00000163251
FZD9 GeneProduct ensembl:ENSG00000188763
FZD2 GeneProduct ensembl:ENSG00000180340
SFRP1 GeneProduct ensembl:ENSG00000104332
SFRP2 GeneProduct ensembl:ENSG00000145423
SFRP4 GeneProduct ensembl:ENSG00000106483
SFRP5 GeneProduct ensembl:ENSG00000120057
WNT3A GeneProduct ensembl:ENSG00000154342
WNT7A GeneProduct ensembl:ENSG00000154764
WNT11 GeneProduct ensembl:ENSG00000085741
WNT1 GeneProduct ensembl:ENSG00000125084
WNT5B GeneProduct ensembl:ENSG00000111186
WNT2 GeneProduct ensembl:ENSG00000105989
WNT2B GeneProduct ensembl:ENSG00000134245
WNT6 GeneProduct ensembl:ENSG00000115596
WNT5A GeneProduct ensembl:ENSG00000114251
WNT16 GeneProduct ensembl:ENSG00000002745
WNT4 GeneProduct ensembl:ENSG00000162552
WNT3 GeneProduct ensembl:ENSG00000108379
WNT10B GeneProduct ensembl:ENSG00000169884
WNT7B GeneProduct ensembl:ENSG00000188064
WNT10A GeneProduct ensembl:ENSG00000135925
WNT16 GeneProduct ensembl:ENSG00000002745
ROR1 GeneProduct ensembl:ENSG00000185483
RYK GeneProduct ensembl:ENSG00000163785
ROR2 GeneProduct ensembl:ENSG00000169071
LRP5 GeneProduct ensembl:ENSG00000162337
LRP6 GeneProduct ensembl:ENSG00000070018
KREMEN1 GeneProduct ensembl:ENSG00000183762
FRAT1 GeneProduct ensembl:ENSG00000165879
GSK3B GeneProduct ensembl:ENSG00000082701
CSNK2B GeneProduct ensembl:ENSG00000204435
APC GeneProduct ensembl:ENSG00000134982
CSNK1E GeneProduct ensembl:ENSG00000213923
CTNNB1 GeneProduct ensembl:ENSG00000168036
CSNK1A1 GeneProduct ensembl:ENSG00000113712
CSNK2A1 GeneProduct ensembl:ENSG00000101266
AXIN1 GeneProduct ensembl:ENSG00000103126
CSNK1A1L GeneProduct ensembl:ENSG00000180138
CSNK2A3 GeneProduct ensembl:ENSG00000254598
CSNK2A2 GeneProduct ensembl:ENSG00000070770
CTNNB1 GeneProduct ensembl:ENSG00000168036
FRAT2 GeneProduct ensembl:ENSG00000181274
CXXC4 GeneProduct ensembl:ENSG00000168772
SENP2 GeneProduct ensembl:ENSG00000163904
DVL3 GeneProduct ensembl:ENSG00000161202
DVL2 GeneProduct ensembl:ENSG00000004975
DVL1 GeneProduct ensembl:ENSG00000107404
26S Proteasome Degradation Pathway wikipathways:WP183
CTNNB1 GeneProduct ensembl:ENSG00000168036
LEF1 GeneProduct ensembl:ENSG00000138795
TCF7L2 GeneProduct ensembl:ENSG00000148737
CTNNB1 GeneProduct ensembl:ENSG00000168036
CHD8 GeneProduct ensembl:ENSG00000100888
SOX17 GeneProduct ensembl:ENSG00000164736
CTBP1 GeneProduct ensembl:ENSG00000159692
CTBP2 GeneProduct ensembl:ENSG00000175029
PLAU GeneProduct ensembl:ENSG00000122861
CCND1 GeneProduct ensembl:ENSG00000110092
JUN GeneProduct ensembl:ENSG00000177606
CCND3 GeneProduct ensembl:ENSG00000112576
FOSL1 GeneProduct ensembl:ENSG00000175592
MYC GeneProduct ensembl:ENSG00000136997
CCND2 GeneProduct ensembl:ENSG00000118971
PIK3CA GeneProduct ensembl:ENSG00000121879
PIK3CB GeneProduct ensembl:ENSG00000051382
PIK3CD GeneProduct ensembl:ENSG00000171608
RPS6KB1 GeneProduct ensembl:ENSG00000108443
RPS6KB2 GeneProduct ensembl:ENSG00000175634
EIF4B GeneProduct ensembl:ENSG00000063046
RPS6 GeneProduct ensembl:ENSG00000137154
PIK3CG GeneProduct ensembl:ENSG00000105851
AKT1 GeneProduct ensembl:ENSG00000142208
AKT3 GeneProduct ensembl:ENSG00000117020
AKT2 GeneProduct ensembl:ENSG00000105221
PI3K-Akt signaling pathway Pathway wikipathways:WP4172
ERK2 GeneProduct ensembl:ENSG00000100030
JAK/STAT pathway Pathway wikipathways:WP2593
MAP2K2 GeneProduct ensembl:ENSG00000126934
MAP2K7 GeneProduct ensembl:ENSG00000076984
MAP2K3 GeneProduct ensembl:ENSG00000034152
MAP3K1 GeneProduct ensembl:ENSG00000095015
MAP3K2 GeneProduct ensembl:ENSG00000169967
MAP3K3 GeneProduct ensembl:ENSG00000198909
MAP3K4 GeneProduct ensembl:ENSG00000085511
MAP3K6 GeneProduct ensembl:ENSG00000142733
MAP3K10 GeneProduct ensembl:ENSG00000130758
MAP3K11 GeneProduct ensembl:ENSG00000173327
MEF2D GeneProduct ensembl:ENSG00000116604
ATF2 GeneProduct ensembl:ENSG00000115966
STAT1 GeneProduct ensembl:ENSG00000115415
CREB1 GeneProduct ensembl:ENSG00000118260
RPS6KA5 GeneProduct ensembl:ENSG00000100784
ELK1 GeneProduct ensembl:ENSG00000126767
MAX GeneProduct ensembl:ENSG00000125952
HMGN1 GeneProduct ensembl:ENSG00000205581
DDIT3 GeneProduct ensembl:ENSG00000175197
MKNK2 GeneProduct ensembl:ENSG00000099875
MAPKAPK2 GeneProduct ensembl:ENSG00000162889
RPS6KA5 GeneProduct ensembl:ENSG00000100784
MKNK1 GeneProduct ensembl:ENSG00000079277
MKNK2 GeneProduct ensembl:ENSG00000099875
RPS6KA3 GeneProduct ensembl:ENSG00000177189
RPS6KB1 GeneProduct ensembl:ENSG00000108443
RPS6KB2 GeneProduct ensembl:ENSG00000175634
RPTOR GeneProduct ensembl:ENSG00000141564
PRAS40 GeneProduct ensembl:ENSG00000204673
TEL2 GeneProduct ensembl:ENSG00000100726
TTI1 GeneProduct ensembl:ENSG00000101407
MLST8 GeneProduct ensembl:ENSG00000167965
DEPTOR GeneProduct ensembl:ENSG00000155792
MTOR GeneProduct ensembl:ENSG00000198793
RPTOR GeneProduct ensembl:ENSG00000141564
MYC GeneProduct ensembl:ENSG00000136997
CIT GeneProduct ensembl:ENSG00000122966
TNNT1 GeneProduct ensembl:ENSG00000105048
ADAMTS1 GeneProduct ensembl:ENSG00000154734
MAD2L1 GeneProduct ensembl:ENSG00000164109
UHRF1 GeneProduct ensembl:ENSG00000276043
PRSS23 GeneProduct ensembl:ENSG00000150687
KIF23 GeneProduct ensembl:ENSG00000137807
PODXL GeneProduct ensembl:ENSG00000128567
TRAF2 GeneProduct ensembl:ENSG00000127191
MDK GeneProduct ensembl:ENSG00000110492
SELE GeneProduct ensembl:ENSG00000007908
CTHRC1 GeneProduct ensembl:ENSG00000164932
DSC3 GeneProduct ensembl:ENSG00000134762
Ca2+ Metabolite chebi:29108
Ca2+ Metabolite chebi:29108
CYCS GeneProduct ensembl:ENSG00000172115
BARD1 GeneProduct ensembl:ENSG00000138376
BRCA1 GeneProduct ensembl:ENSG00000012048
14-3-3 Protein uniprot:A0A0J9YWE8
HCFC1 GeneProduct ensembl:ENSG00000172534
OGT GeneProduct ensembl:ENSG00000147162
HCFC1 GeneProduct ensembl:ENSG00000172534
Gluconeogenesis Pathway wikipathways:WP534

References

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