Tryptophan metabolism (WP79)

This pathway describes the metabolism of tryptophan, an essential amino acid. Originally converted from rat to human using ortholog information. Edited by Sebastien Burel
last edited

Authors

L.M.Ferrante, MaintBot, Khanspers, Egonw, Ddigles, AlexanderPico, and Fehrhart

Cited In

Organism

Mus musculus

Communities

Annotations

Pathway Ontology: tryptophan metabolic pathway

Participants

Label Type Compact Identifier
4-(2-Aminophenyl)-2,4-dioxobutanoate Metabolite chebi:58147
Indolelactate Metabolite pubchem.compound:92904
2-Aminomuconate Metabolite chemspider:27
3-Methylindolepyruvate Metabolite pubchem.compound:440740
7,8-Dihydro-7,8-dihydroxykynurenate Metabolite chemspider:388563
Indole-3-acetate Metabolite chemspider:780
N-Methylserotonin Metabolite pubchem.compound:150885
C00877 Metabolite kegg.compound:C00877
N-Methyltryptamine Metabolite chebi:28136
4,8-Dihydroxyquinoline Metabolite chebi:28883
4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate Metabolite chemspider:389617
Oxaloacetate Metabolite chebi:16452
3-(2-Aminoethyl)-1H-indol-5-ol Metabolite pubchem.compound:5202
Indolepyruvate Metabolite pubchem.compound:803
Melatonin Metabolite pubchem.compound:896
Indole-3-acetaldehyde Metabolite chebi:18086
Glucobrassicin Metabolite chebi:29028
Kynurenate Metabolite chebi:18344
C00527 Metabolite kegg.compound:C00527
Formylanthranilate Metabolite chebi:18410
3-Hydroxy-L-kynurenine Metabolite chebi:17380
5-Methoxyindoleacetate Metabolite pubchem.compound:18986
3-Methyldioxyindole Metabolite chebi:28254
2-Aminomuconate Metabolite chemspider:27
C01144 Metabolite kegg.compound:C01144
5-Hydroxyindoleacetaldehyde Metabolite pubchem.compound:74688
3-Hydroxyanthranilate Metabolite chemspider:7822291
Indole-3-acetaldoxime Metabolite chebi:28311
5-Hydroxy-N-formylkynurenine Metabolite chemspider:389615
Isophenoxazine Metabolite chemspider:65565
5-(2-Carboxyethyl)-4,6-dihydroxypicolinate Metabolite Chemspider
Indole-3-ethanol Metabolite pubchem.compound:10685
6-Hydroxyindolelactate Metabolite chebi:27524
Anthranilate Metabolite chebi:16567
5-Hydroxykynurenamine Metabolite chemspider:144400
Anthranilate Metabolite chebi:16567
5-(3-Carboxy-3-oxopropenyl)-4,6-dihydroxypicolin Metabolite None
2-Formylaminobenzaldehyde Metabolite chebi:18033
2-Formaminobenzoylacetate Metabolite None
4,6-Dihydroxyquinoline Metabolite chemspider:389609
L-Tryptophanyl-tRNA Unknown None
2,3-Dihydroxyindole Metabolite chebi:17828
Quinolinate Metabolite chemspider:2777129
Cinnavalininate Metabolite chemspider:102864
5-Hydroxy-L-tryptophan Metabolite chebi:17780
3-Hydroxykynurenamine Metabolite chemspider:144400
Formyl-5-hydroxykynurenamine Metabolite pubchem.compound:440743
5-Hydroxyindolepyruvate Metabolite chemspider:389613
3-Methoxyanthranilate Metabolite chebi:20109
2-Oxoglutarate Metabolite chebi:30916
N-Acetylindoxyl Metabolite chebi:15363
2-Oxoadipate Metabolite chemspider:70
7,8-Dihydroxykynurenate Metabolite chebi:58171
Xanthurenic Metabolite chemspider:5497
5-Hydroxyindoleacetate Metabolite pubchem.compound:1826
C00332 Metabolite kegg.compound:C00332
5-(3-Carboxy-3-oxopropyl) -4,6-dihydroxypicolinate Metabolite chemspider:389620
(Z)-5-Oxohex-2-enedioate Metabolite chebi:16967
5-(2-Formylethyl)-4,6-dihydroxypicolinate Metabolite Chemspider
Formyl-N-acetyl-5-methoxykynurenamine Metabolite pubchem.compound:171161
3-Indoleglycolaldehyde Metabolite chebi:15976
8-Methoxykynurenate Metabolite chebi:20109
2-Amino-3-carboxymuconate Metabolite None
6-Hydroxykynurenate Metabolite chemspider:389622
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate Metabolite None
5-Hydroxyindoleacetylglycine Metabolite pubchem.compound:440806
Cyp4f14 GeneProduct ncbigene:64385
Ubr5 GeneProduct ncbigene:70790
4.2.1.84 GeneProduct None
Ido1 GeneProduct ncbigene:15930
Cyp2e1 GeneProduct ncbigene:13106
Rnf25 GeneProduct ncbigene:57751
Gcdh GeneProduct ncbigene:270076
Aldh9a1 GeneProduct ncbigene:56752
Prmt1 GeneProduct ncbigene:15469
Aldh2 GeneProduct ncbigene:11669
Aldh1a2 GeneProduct ncbigene:19378
Formylkynurenine Metabolite chebi:30249
2.6.1.27 GeneProduct None
4.1.1.- GeneProduct None
1.13.11.10 GeneProduct None
Cyp2d2 GeneProduct None
ASMT GeneProduct ncbigene:107626
Acetyl-CoA Metabolite chebi:15351
1.14.16.- GeneProduct None
Indole Metabolite pubchem.compound:798
1.5.1.- GeneProduct None
Cyp1a1 GeneProduct ncbigene:13076
Mdm2 GeneProduct ncbigene:17246
Ogdh GeneProduct ncbigene:18293
1.7.3.2 GeneProduct None
Maob GeneProduct ncbigene:109731
Aldh3a2 GeneProduct ncbigene:11671
Maob GeneProduct ncbigene:109731
Ddc GeneProduct ncbigene:13195
Hsd17b10 GeneProduct ncbigene:15108
Aldh9a1 GeneProduct ncbigene:56752
Cat GeneProduct ncbigene:12359
Ube3a GeneProduct ncbigene:22215
5-Methoxytryptamine Metabolite chebi:2089
1.13.11.- GeneProduct None
Hadh GeneProduct ncbigene:15107
CYP3A4 GeneProduct None
Aldh3a2 GeneProduct ncbigene:11671
2.1.1.47 GeneProduct None
Ddc GeneProduct ncbigene:13195
1.13.11.23 GeneProduct None
Ddc GeneProduct ncbigene:13195
Aldh2 GeneProduct ncbigene:11669
Maob GeneProduct ncbigene:109731
1.1.1.110 GeneProduct None
1.2.3.7 GeneProduct None
Mdm2 GeneProduct ncbigene:17246
Cyp7b1 GeneProduct ncbigene:13123
Ube3a GeneProduct ncbigene:22215
Aadat GeneProduct ncbigene:23923
1.10.3.4 GeneProduct None
Acat1 GeneProduct ncbigene:110446
Ido1 GeneProduct ncbigene:15930
Aldh1a2 GeneProduct ncbigene:19378
4.1.1.43 GeneProduct None
L-Kynurenine Metabolite chebi:16946
Kynu GeneProduct ncbigene:70789
1.14.99.2 GeneProduct None
Afmid GeneProduct ncbigene:71562
Cyp1b1 GeneProduct ncbigene:13078
2.6.1.27 GeneProduct None
1.13.11.17 GeneProduct None
Aanat GeneProduct ncbigene:11298
1.2.1.32 GeneProduct None
Aox1 GeneProduct ncbigene:11761
Dhcr24 GeneProduct ncbigene:74754
3.2.1.147 GeneProduct None
4.1.99.1 GeneProduct None
5-Hydroxykynurenine Metabolite chemspider:389616
Aadat GeneProduct ncbigene:23923
Acmsd GeneProduct ncbigene:266645
Ido1 GeneProduct ncbigene:15930
1.14.13.9 GeneProduct None
Tryptamine Metabolite chebi:16765
3.5.99.5 GeneProduct None
Kynu GeneProduct ncbigene:70789
Cyp1a2 GeneProduct ncbigene:13077
Cyp2c55 GeneProduct ncbigene:72082
Cyp2b15 GeneProduct None
Wars GeneProduct ncbigene:22375
N-Acetylisatin Metabolite chebi:16050
CYP2A13 GeneProduct None
Aldh1a4 GeneProduct None
Inmt GeneProduct ncbigene:21743
Cyp19a1 GeneProduct ncbigene:13075
L-Tryptophan Metabolite pubchem.compound:6305
Prmt1 GeneProduct ncbigene:15469
Indole-3-acetamide Metabolite chebi:16031
1.1.1.190 GeneProduct None
Aldh1a1 GeneProduct ncbigene:11668
3.5.1.49 GeneProduct None
3.5.5.1 GeneProduct None
Cyp2j6 GeneProduct ncbigene:13110
Cyp2c12 GeneProduct None
3.5.1.4 GeneProduct None
Haao GeneProduct ncbigene:107766
3-Indoleacetonitrile Metabolite chebi:17566
Prmt1 GeneProduct ncbigene:15469
1.3.1.18 GeneProduct None
Abp1 GeneProduct ncbigene:76507
1.4.3.2 GeneProduct None
Rnf25 GeneProduct ncbigene:57751
Maob GeneProduct ncbigene:109731
Kynu GeneProduct ncbigene:70789
Cyp2a1 GeneProduct None
2-Aminophenol Metabolite chebi:18112
2.1.1.49 GeneProduct None
Mdm2 GeneProduct ncbigene:17246
1.14.16.3 GeneProduct None
Echs1 GeneProduct ncbigene:93747
Tdo2 GeneProduct ncbigene:56720
Cyp2f2 GeneProduct ncbigene:13107
Gcdh GeneProduct ncbigene:270076
Tph1 GeneProduct ncbigene:21990
6-Hydroxymelatonin Metabolite pubchem.compound:1864
Aldh1a4 GeneProduct None
2.6.1.27 GeneProduct None
1.2.1.- GeneProduct None
N-Acetylserotonin Metabolite chebi:17697
1.13.12.3 GeneProduct None
Aldh1a1 GeneProduct ncbigene:11668
1.13.99.3 GeneProduct None
Cyp2a2 GeneProduct None
ASMT GeneProduct ncbigene:107626
3.5.1.9 GeneProduct None
1.1.1.191 GeneProduct None

References